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The role of SYNE1/2 variants as a potential predisposition factor for the onset of endometriosis.

Endometriosis (EM) is a chronic, inflammatory gynaecological disorder defined by the presence of endometrial-like tissue outside the uterine cavity, most frequently affecting the ovaries, peritoneum, and uterosacral ligaments. Despite its …

Published: Aug. 25, 2026, midnight
Icaritin improves pregnancy outcomes in endometriosis by inhibiting ovarian granulosa cell senescence.

Endometriosis (EMS) is an oestrogen-dependent chronic inflammatory disease that primarily manifests as chronic pelvic pain and infertility. EMS-associated infertility is closely linked to diminished ovarian function and oocyte quality, with …

Published: Aug. 21, 2026, midnight
Effects of strength training on physical fitness and perceived health in women with endometriosis.

This study aimed to evaluate the impact of an 8 weeks functional strength training program on physical performance, pain perception, and quality of life in women with endometriosis.

Published: Aug. 20, 2026, midnight
Deep infiltrating endometriosis-related quality of life after laparoscopic excision: A prospective cohort study from Latin America using validated questionnaires.

Deep infiltrating endometriosis (DIE) is associated with substantial impairment in health-related quality of life (HRQoL), affecting pain, emotional well-being, sexual functioning, and daily activities. Previous studies have shown that laparoscopic …

Published: Aug. 20, 2026, midnight
Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.

Endometriosis, defined as the ectopic growth of endometrial tissue outside of the uterine cavity, is an inflammatory and hormone-dependent disease that causes excruciating pelvic pain, infertility, and significantly decreases quality …

Published: Aug. 19, 2026, midnight
Endometriosis-associated bone loss: re-evaluating the potential role of systemic inflammation and hypoestrogenic therapies.

Endometriosis is frequently managed with hormonal suppression that can induce hypoestrogenism during a period when many patients are still accruing peak bone mass. This narrative review summarizes current clinical and …

Published: Aug. 19, 2026, midnight
Exploring the exercise dose to induce symptomatic and biomarker change in endometriosis: A protocol for a randomised controlled trial.

Exercise may be an effective tool to improve symptoms and quality of life in those with endometriosis. However, the optimal dose to elicit such changes is unknown. This study will …

Published: Aug. 19, 2026, midnight
Diet and physical activity coaching for well-being and pain reduction in patients with symptomatic endometriosis: a randomized-controlled clinical trial.

Pain is a defining symptom of endometriosis reducing quality of life and increasing the risk of psychological disorders. We conducted an open-label, randomized, controlled trial to investigate whether structured coaching …

Published: Aug. 17, 2026, midnight
Reframing endometriosis care in low-resource settings: a pragmatic 5R framework for recognition, rule-out, relief, referral and review.

Endometriosis is a chronic inflammatory gynecological condition associated with severe dysmenorrhea, chronic pelvic pain, deep dyspareunia, cyclic bowel or urinary symptoms and infertility. It is also linked to psychological morbidity, …

Published: Aug. 17, 2026, midnight
Effect of deoxyribonuclease I therapy on free circulating DNA level and gene methylation profile changes in patients with endometriosis: Proof of concept and preliminary data.

ObjectiveEndometriosis is a systemic chronic disease with serious effects on various aspects of female health and wellbeing that has been associated with a significant increase in free circulating DNA (CfDNA) …

Published: Aug. 14, 2026, midnight
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