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An ultrasound-based machine learning model for predicting pelvic adhesions: A SHAP-enhanced XGBoost approach.

This study is the first to develop and evaluate a machine learning (ML) model for predicting pelvic adhesions based on ultrasound features, utilizing the SHapley Additive Explanations (SHAP) framework for …

Published: Jan. 19, 2026, midnight
Lifestyle and Selected Issues Related to Sexual Health: The Importance of Specialist Care in Balneology, Dietetics, and Physiotherapy.

Background/Objectives: Sexual health is shaped by lifestyle factors alongside biomedical determinants. This review synthesises evidence on physiotherapy, balneology/peloidotherapy, and diet therapy as preventive and therapeutic adjuncts for female sexual dysfunctions …

Published: Dec. 31, 2025, midnight
In Situ Characterization and Deep Profiling of Engineered Multispecific Nanoparticle Metabolite Coronas for Precise Serum Diagnostics.

Upon exposure to biofluids, engineered nanoparticles (NPs) spontaneously form reproducible biomolecular coronas via selective diverse biomolecule adsorption. The corona characterization of metabolites poses greater analytical challenges than proteins due to …

Published: Dec. 26, 2025, midnight
Gender-Based Violence Among People With Disabilities: Qualitative Insights on Sexual and Reproductive Health Impacts Across the Life Course.

Women and gender-diverse people with disabilities are at an elevated risk of gender-based violence (GBV). This study examines how women and gender-diverse people with disabilities experience GBV and how such …

Published: Dec. 10, 2025, midnight
Microbiota insights in endometriosis.

Endometriosis affects approximately 10% of women of reproductive age and is characterized by the presence of endometrial-like tissue outside the uterine cavity, leading to chronic pelvic pain, infertility, and a …

Published: Dec. 5, 2025, midnight
The role of pharmacotherapy in the treatment of endometriosis: an update.

Endometriosis is a chronic inflammatory condition affecting ~10% of reproductive-age individuals and contributing significantly to infertility, pain, and reduced quality of life. Since our 2020 review, new pharmacologic strategies, updated …

Published: Dec. 2, 2025, midnight
Integrating inflammatory biomarkers and demographic variables with machine learning to predict endometriosis risk.

This study explores the relationship between inflammatory biomarkers and the risk of endometriosis, aiming to develop a predictive model using National Health and Nutrition Examination Survey (1999-2006) data. The dataset …

Published: Nov. 27, 2025, midnight
Establishment of immortalized ovarian stromal cell lines using Sendai virus vectors: a platform for studying tumor-stroma interactions and carcinogenesis.

We aimed to generate immortalized stromal cell lines from the ovarian and fallopian tube tissues of a single patient using Sendai virus (SeV) vectors and identify candidate stromal genes involved …

Published: Nov. 26, 2025, midnight
Personalized Vaginal Drug Delivery through 3D Printing: Techniques, Challenges, and Future Perspectives.

Vaginal disorders in reproductive‑age women, including bacterial vaginosis (affecting 23-29%), endometriosis, etc., are increasing alarmingly day by day worldwide. Vaginal drug delivery (VDD) has garnered notable attention in the pharmaceutical …

Published: Nov. 26, 2025, midnight
Hormonal imbalance in umbilical vein cord blood of pregnant women with endometriosis: a propensity score-matched analysis.

Pregnancy involves a fine-tuned hormonal interplay between the fetus, placenta, and mother, which shapes long-term developmental outcomes. Endometriosis has been hypothesized to originate in utero due to altered fetal exposure …

Published: Nov. 25, 2025, midnight
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