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Infertility management in patients with bowel endometriosis: the current landscape and the promise of randomised trials: a narrative review.

The management of infertility in women with bowel endometriosis remains a significant clinical challenge. The two primary therapeutic approaches include first-line medically assisted reproduction (MAR) and primary bowel surgery, with …

Published: Dec. 3, 2025, midnight
Pain, emotional distress, and fear of recurrence or progression in people with endometriosis: a network approach.

Pain is a common debilitating symptom reported in people with endometriosis. Yet, we do not have a good understanding of factors that may contribute to higher pain and worse psychosocial …

Published: Dec. 2, 2025, midnight
The pelvic pain bias assessment: a new assessment of interpretation bias specific to pelvic pain.

Pelvic pain is a common and often debilitating experience with limited treatment options. Improving understanding of the psychosocial mechanisms involved in pelvic pain experiences will enhance the efficacy of pain …

Published: Dec. 2, 2025, midnight
High inhibition ratio and transformation index of 2 mg dienogest: further evidence for its use in endometriosis treatment.

Endometriosis is a common, chronic disease with a high burden for women, characterised by the implantation of endometrial cells outside the uterus. Many different treatments have been proposed for this …

Published: Dec. 2, 2025, midnight
ZMIZ1 and estrogen receptor α form an essential partnership in endometrial biology.

Estrogen receptor α (ESR1) is a pivotal regulator of endometrial homeostasis and reproductive function, yet the coregulators that fine tune its transcriptional activity remain incompletely defined. In this issue of …

Published: Dec. 1, 2025, midnight
Racial and Ethnic Inequities in Rates of Diagnostic Laparoscopy for Evaluation of Endometriosis in Adolescents with Pelvic Pain: a Retrospective Cohort Study.

Endometriosis often presents in adolescence as chronic pelvic pain (CPP) or dysmenorrhea. Research in adults demonstrates non-White race is associated with delayed surgical diagnosis of endometriosis; however, inequity in adolescents …

Published: Dec. 1, 2025, midnight
Biochemical Heterogeneity of Endometriosis Phenotypes Revealed by FTIR Analysis.

Fourier-transform infrared (FTIR) spectroscopy was used to investigate molecular differences among peritoneal, ovarian, bowel endometriosis phenotypes and control tissues. Peritoneal lesions showed the most pronounced spectral changes in CH-stretching (2800-3000 …

Published: Nov. 30, 2025, midnight
Uterine artery S/D ratio and serum CA125 as predictors of early pregnancy loss in women with ovarian endometriomas: a retrospective case-control study.

Endometriosis affects approximately 10% of women of reproductive age and is associated with increased risks of infertility and miscarriage. Although the spontaneous miscarriage rate in women with endometriosis is higher …

Published: Nov. 29, 2025, midnight
Exploring the impact of dietary theobromine on endometriosis risk: Evidence from Mendelian randomization and NHANES data.

Endometriosis is a chronic inflammatory estrogen-dependent inflammatory disorder. Theobromine has been implicated in diverse health benefits, including anti-inflammatory and vasodilatory properties. However, the precise association between theobromine and endometriosis remains …

Published: Nov. 28, 2025, midnight
S1P3 Receptor Mediates the Proinflammatory Effect of the Endocannabinoid 2-Arachidonoylglycerol in Endometriotic Epithelial Cells.

Endometriosis is a chronic inflammatory disease characterized by the ectopic implantation of endometrium outside the uterus associated with pelvic pain and infertility. The molecular mechanisms involved in the pathogenesis of …

Published: Nov. 27, 2025, midnight
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