The human microbiome, a dynamic endocrine organ, exerts profound systemic influence through the production of bioactive metabolites. While the microbiome-gut-brain axis is well-established, the direct conduit between the gut microbiota …
Introduction. Endometriosis affects 10-20% of reproductive-age women. Emerging evidence links the gut microbiota to endometriosis pathogenesis, but observational studies are limited by confounding, reverse causation and uncertainty about whether reported …
The "gut microbiota-mitochondria axis" has become the core hub connecting the metabolism, immunity, and endocrine regulation of gynecological diseases. In this review, the hierarchical regulation mechanism of this axis is …
Natural bioactive compounds, such as curcumin, polyphenols, and flavonoids are important in the prevention and treatment of lifestyle disorders like diabetes, cancer, and heart disease. Their immunomodulatory, antiviral, antioxidant, and …
The female reproductive tract (FRT), particularly the vagina, has traditionally been regarded as a sterile environment. However, it is now recognized that the vagina is a complex, dynamic ecosystem dominated …
Emerging signal transduction pathways and the role of bacterial extracellular vesicles linked to the pathogenesis of endometriosis Nature
Endometriosis is defined as the ectopic proliferation of endometrial cells. Aberrant signal transduction is present in ectopic endometriotic lesions, and bacteria also contributes to the development of endometriosis by transmitting …
Quercetin is a naturally occurring flavonoid found in fruits, vegetables, and teas that is widely available as a dietary supplement. Numerous studies have investigated quercetin's therapeutic potential across a broad …
This case-control study investigated whether ovarian endometriosis is associated with altered estrogen metabolism and gut or urogenital microbiota by analyzing enzyme activity, bacterial composition, and variations of estrogen metabolites in …
What If Endometriosis Is Not Just Hormonal? Scientists Are Looking at Bacteria fiercebymitu.com