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A transcriptomics-based computational drug repurposing pipeline identifies simvastatin and primaquine as therapeutics for endometriosis.

Endometriosis has limited treatment options, prompting the search for data-driven therapeutics. We previously used a transcriptomics-based computational drug repositioning pipeline and identified several drug candidates. Fenoprofen, our top in silico …

Published: Aug. 21, 2026, midnight
Endometriosis Longitudinal Fertility Study (ELFS): a prospective longitudinal cohort study of the effect of conservative and surgical management for moderate to severe endometriosis on future fertility - study protocol.

Endometriosis is associated with reduced pregnancy and live birth rates in patients attempting both spontaneous and assisted conception. At present, it is unclear whether prepregnancy surgery for moderate or severe …

Published: Aug. 20, 2026, midnight
Deep infiltrating endometriosis-related quality of life after laparoscopic excision: A prospective cohort study from Latin America using validated questionnaires.

Deep infiltrating endometriosis (DIE) is associated with substantial impairment in health-related quality of life (HRQoL), affecting pain, emotional well-being, sexual functioning, and daily activities. Previous studies have shown that laparoscopic …

Published: Aug. 20, 2026, midnight
Body image concerns, disordered eating, and negative affect in women with and without gynecological conditions.

BackgroundResearch has suggested that some gynecological conditions are associated with body image, disordered eating behaviors, and mental health concerns. This has been studied in polycystic ovarian syndrome and endometriosis populations, …

Published: Aug. 17, 2026, midnight
Exploring the Possible Role of Endometriosis-Associated Dysbiosis in Endometrial Carcinogenesis.

Background and Objectives: Endometriosis is associated with chronic inflammation, immune dysregulation, oestrogen-dependent growth, oxidative stress, altered steroid hormone metabolism, compromised epithelial barrier integrity, and the production of bioactive microbial metabolites. …

Published: Aug. 17, 2026, midnight
Complementary roles of rectal magnetic resonance imaging and endoscopic ultrasound in the preoperative assessment of rectal deep endometriosis: a retrospective cohort.

To investigate the complementary roles of rectal magnetic resonance imaging and endoscopic ultrasound in the preoperative assessment of rectal deep endometriosis.

Published: Aug. 14, 2026, midnight
A retrospective cohort study comparing controlled ovarian stimulation protocols for IVF/ICSI in women with endometriosis and diminished ovarian reserve.

Assisted reproductive treatment for women with endometriosis and diminished ovarian reserve (DOR) is challenging, and the optimal controlled ovarian stimulation (COS) protocol for this population remains uncertain. This study compared …

Published: Aug. 14, 2026, midnight
Exosomal miR-21-5p from ectopic endometrial stromal cells drives fibrosis progression in endometriosis through direct VHL targeting.

Ovarian endometriosis is a chronic inflammatory disease characterized by extensive tissue remodeling and fibrosis, which significantly impacts female reproductive health. This study demonstrates that ectopic endometrium (Ect) in patients with …

Published: Aug. 12, 2026, midnight
Obstetric Complications in Pregnant Women with and without Endometriosis: A Comparative Cohort Study.

Since the complications associated with endometriosis during pregnancy are rare, there is not enough evidence to indicate that this disease has major detrimental effects on pregnancy outcome. Therefore, the present …

Published: Aug. 8, 2026, midnight
Video-Based Assessment of Operative Complexity in Endometriosis: Associations of AAGL 2021, #Enzian, and rASRM Classifications with Operative Time and Advanced Surgical Procedures.

To evaluate how the AAGL 2021, #Enzian, and revised American Society for Reproductive Medicine (rASRM) classifications reflect operative time, advanced surgical procedures, and blood-loss-related perioperative outcomes in a video-reassessed cohort …

Published: Aug. 7, 2026, midnight
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