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Why does surgery for endometriosis-associated infertility often fail to improve pregnancy outcome?

Endometriosis can impair natural reproduction through multiple mechanisms, including distortion of pelvic anatomy and chronic peritoneal inflammation. On this basis, surgical treatment might be reasonably expected to benefit. However, clinical …

Published: March 5, 2026, midnight
Comparison Between Catheter-Directed Sclerotherapy and Surgical Removal of Large Ovarian Endometriomas: A Retrospective, Single-Center Observational Study.

Background/Objectives: The treatment options for endometriosis vary depending on individual needs and clinical circumstances. To preserve ovarian reserve, ethanol catheter-directed sclerotherapy may be considered as a treatment option. We compared …

Published: March 4, 2026, midnight
Differential expression of c-kit, E-cadherin, and beta-catenin in endometriosis and normal endometrial tissue.

C-kit, E-cadherin and beta-catenin adhesion molecules and proto-oncogenes are thought to be associated with molecular mechanisms related to the invasion, implantation and persistence of ectopic endometrial cells. Comparing the expression …

Published: March 2, 2026, midnight
Three-dimensional patient-derived endometriosis model for drug evaluation.

Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms. Its pathogenesis remains unknown, and there is no effective treatment. Therefore, establishing patient-derived models is crucial for …

Published: March 2, 2026, midnight
Bladder Endometriosis Resolved by Robotic-Assisted Partial Cystectomy.

This is a case report of a 31-year-old G1P1 with deep infiltrating endometriosis (DIE) of the bladder. She presented with bladder spasms, dysuria, and urinary frequency that worsened during her …

Published: March 2, 2026, midnight
Integrating ultrasound findings and extreme CA-125 elevation in the diagnosis of spontaneous endometrioma rupture: a case report.

Introduction: Spontaneous rupture of an endometrioma may result in life-threatening condition. Detection and prompt treatment are necessary. Presentation of Case: A 27-year-old woman presented to labor and delivery unit with …

Published: Feb. 28, 2026, midnight
Endometriomas are heterogeneous for functional FSH receptor expression and steroidogenic function.

We investigated whether ovarian endometriomas uniformly express functional FSH receptors (FSHR) and respond to FSH by activating transcriptional programs that drive aromatase and steroid hormone production. Endometrioma cyst capsules were …

Published: Feb. 27, 2026, midnight
Deep-Infiltrating Endometriosis Causing Acute Mechanical Intestinal Obstruction Without Intestinal Invasion: A Case Report with Diagnostic and Surgical Insights.

Endometriosis is a chronic, estrogen-dependent disorder that may extend beyond the pelvis to involve the gastrointestinal tract, most commonly the rectosigmoid and, less frequently, the small bowel. Although often asymptomatic, …

Published: Feb. 23, 2026, midnight
Investigating Unilateral Ovarian Endometrioma's Effect on Ova and Embryo Quality in 409 Infertile Endometriotic Patients.

In women with unilateral endometriosis, how do ovarian endometriomas and their inflammatory content affect oocyte and embryo quality in affected versus healthy ovaries, and what is the impact on ART …

Published: Feb. 22, 2026, midnight
Fertility preservation in women with endometriosis: How, when, and for whom?

Fertility preservation options, including cryopreservation of oocytes, embryos, and ovarian tissue, were initially focused on women undergoing gonadotoxic chemotherapy for oncologic treatment. The indications have expanded to include nonmalignant conditions …

Published: Feb. 20, 2026, midnight
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