Lipidomics, an emerging field in medical research, has deepened our understanding of lipid metabolism, signal transduction pathways, and intercellular communication through qualitative and quantitative analyses of patient lipid profiles. It …
As a gynecological disease, endometriosis is a disease in which pain and inflammation are important parts. Endometriosis is a chronic, estrogen-related situation with a multifactorial etiology that remains incompletely understood. …
Gynecological diseases (GyD) are related to reproductive tissue disorders such as the cervix, vagina, fallopian tubes, and ovaries, which can affect fertility. Among these diseases, we can mention endometriosis, ovarian …
Endometriosis is a chronic gynecological disease affecting 1 in 10 reproductive-aged women and is characterized by the ectopic presence of endometrial tissue outside the uterus. The leading hypothesis for disease …
The human endometrium is a dynamic tissue that lines the uterus and undergoes constant remodeling, making it especially susceptible to gynecological diseases like endometriosis and endometrial cancer. The molecular mechanisms …
This systematic review aimed to summarize all available data and evaluate the roles of E-cadherin, N-cadherin, associated molecules, and signaling pathways in the pathogenesis of endometriosis. The search was conducted …
The DNA repair enzyme 8-oxoguanine DNA glycosylase-1 (OGG1) plays a crucial role in the initiation of DNA base excision repair pathway by recognizing and excising the oxidative base lesions including …
The global prevalence and trends of gynecological diseases (GDs) among women of childbearing age (WCBA) remain unclear and may be underestimated. This study aims to evaluate the prevalence of GDs …
Background and Clinical Significance: Endometriosis is a common gynecological disease that can occasionally be associated with malignant transformation. The most common site of malignant transformation is the ovary, but there …
Endometriosis is a chronic estrogen-dependent gynecological disease affecting millions of women worldwide. Besides its well-established impact on reproductive health, emerging evidence suggests a potential association between endometriosis and periodontal disease. …