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Identification of potent inhibitors of JUN N-terminal kinases for treatment of endometriosis and associated pain.

Endometriosis, defined as the ectopic growth of endometrial tissue outside of the uterine cavity, is an inflammatory and hormone-dependent disease that causes excruciating pelvic pain, infertility, and significantly decreases quality …

Published: Aug. 19, 2026, midnight
Endometriosis-associated bone loss: re-evaluating the potential role of systemic inflammation and hypoestrogenic therapies.

Endometriosis is frequently managed with hormonal suppression that can induce hypoestrogenism during a period when many patients are still accruing peak bone mass. This narrative review summarizes current clinical and …

Published: Aug. 19, 2026, midnight
Diet and physical activity coaching for well-being and pain reduction in patients with symptomatic endometriosis: a randomized-controlled clinical trial.

Pain is a defining symptom of endometriosis reducing quality of life and increasing the risk of psychological disorders. We conducted an open-label, randomized, controlled trial to investigate whether structured coaching …

Published: Aug. 17, 2026, midnight
Multi-Target Modulation of Interconnected Pathogenetic Pathways by Natural Bioactive Compounds in Endometriosis.

Endometriosis is a chronic estrogen-dependent disease characterized by the presence of endometrial-like tissue outside the uterine cavity. Its pathogenesis involves interactions between inflammatory, angiogenic, hormonal, oxidative stress-related, and cell survival-associated …

Published: Aug. 13, 2026, midnight
Hormonal therapies for endometriosis-associated pain: inflammatory limitations and pharmacological challenges.

Endometriosis is a chronic inflammatory and estrogen-dependent disease in which pain remains the leading cause of impaired quality of life. Hormonal therapies constitute the cornerstone of medical management and include …

Published: Aug. 11, 2026, midnight
Dietary inflammatory index and Mediterranean Diet in female reproductive health: a systematic review and meta-analysis of dietary inflammatory potential.

Female reproductive health is increasingly affected by conditions such as infertility, polycystic ovary syndrome (PCOS), and endometriosis. Given the impact of modifiable lifestyle factors, nutrition has emerged as a potential …

Published: Aug. 11, 2026, midnight
Phthalate exposure and human reproductive health: an epidemiological review.

Plastics are ubiquitous in the environment and are widely used in food packaging, medicine, agriculture, construction and other sectors. However, the plasticizers they contain pose a substantial threat to environmental …

Published: Aug. 9, 2026, midnight
[The Laterality of Endometriosis].

Endometriosis, affecting 10-15% of women of reproductive age, is more commonly found on the left side of the pelvis. This laterality phenomenon's etiology remains obscure. We reviewed the existing literature …

Published: Aug. 7, 2026, midnight
A Mouse Model of Endometriosis Using Ex Vivo Cy5.5 Dye-Doped Silica Nanoparticle Labeling for Lesion Visualization.

Endometriosis is a common gynecological disorder characterized by the growth of endometrial-like tissue outside the uterine cavity, leading to chronic inflammation, pelvic pain, and infertility. Reliable mouse models are essential …

Published: Aug. 4, 2026, midnight
Microplastics and female infertility: reproductive toxicity and underlying mechanisms.

In modern society, the progression of ovarian aging in women has accelerated, and the incidence of infertility has increased markedly with a distinct younger-onset trend. Exploring the etiology and pathogenesis …

Published: Aug. 3, 2026, midnight
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