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Endometriosis-Associated Infertility: A Review of Pathophysiological Mechanisms and Current Treatment Strategies.

Background: Endometriosis affects 10-15% of reproductive-aged women and is a leading cause of infertility through anatomical, inflammatory, and molecular mechanisms. Objective: This review synthesizes current evidence on the pathophysiology of …

Published: June 2, 2026, midnight
Hormonal Dysregulation and Neuroinflammation in Endometriosis: Convergent Druggable Pathways.

Endometriosis is a chronic, estrogen-dependent disorder defined by ectopic endometrial-like tissue growth, persistent inflammation, and aberrant innervation. Emerging evidence indicates that disease progression and symptom severity are driven by a …

Published: May 19, 2026, midnight
Terazosin as a Non-Hormonal Treatment for Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disease including aberrant local steroidogenesis, inflammation, angiogenesis, oxidative stress, and prostaglandin-mediated pain. Given the elevated adrenergic receptor expression in endometriotic lesions and the potential …

Published: May 2, 2026, midnight
Advancing the frontiers of phytotherapy: a comprehensive review of botanical interventions targeting mitochondrial quality control to ameliorate endometriosis.

Endometriosis (EMs) is a gynecological disorder affecting women of reproductive age. It is characterized by the ectopic implantation and infiltration of endometrial-like tissue and is associated with significant effects on …

Published: April 29, 2026, midnight
Pulmonary endometriosis successfully treated with percutaneous radiofrequency ablation: report of two cases.

Pulmonary endometriosis (PE) is an unusual cause of catamenial hemoptysis, with only a small proportion of endometriosis cases involving the thorax. Standard management often involves surgical resection combined with hormonal …

Published: April 28, 2026, midnight
Medical and Surgical Management of Endometriosis: A Narrative Review of Clinical Outcomes.

Endometriosis is a chronic, estrogen-dependent, and heterogeneous gynecologic disorder associated with persistent pain, infertility, and substantial impairment in quality of life (QoL), necessitating individualized and evidence-based management. This narrative review …

Published: April 16, 2026, midnight
Advanced Management of Severe Adenomyosis in IVF: A Personalized Approach With Extended GnRH Agonist and Letrozole Therapy.

The objective of this study is to evaluate the effectiveness of prolonged GnRH agonist (GnRH-a) suppression combined with letrozole and intensive luteal phase support in a patient with severe adenomyosis …

Published: March 9, 2026, midnight
Changing the paradigm of endometriosis - from diagnosis to integrated long-term management: a joint society opinion paper.

Endometriosis is a chronic, systemic, oestrogen-dependent disease with major impacts on pain, fertility and quality of life. This Society of Endometriosis and Uterine Disorders and American Institute for Minimally Invasive …

Published: Feb. 24, 2026, midnight
Endometriosis in adolescents: A state-of-the-art review.

Endometriosis, once considered rare in adolescents, is now recognized as a common cause of chronic pelvic pain and dysmenorrhea in individuals aged 10-21. This state-of-the-art review explores the evolution of …

Published: Jan. 22, 2026, midnight
Macrophages in endometriosis: key roles and emerging therapeutic opportunities-a narrative review.

Endometriosis is a chronic gynecological disorder affecting approximately 10% of women of reproductive age. It commonly presents with pelvic pain, dysmenorrhea, and infertility, imposing substantial physical, psychological, and social burdens. …

Published: Oct. 21, 2025, midnight
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