Plastics are ubiquitous in the environment and are widely used in food packaging, medicine, agriculture, construction and other sectors. However, the plasticizers they contain pose a substantial threat to environmental …
Adult stem cells are thought to drive the regenerative potential of the endometrium and contribute to the pathogenesis of endometriosis; however, their identity and defining features remain to be characterized. …
Endometriosis is a chronic inflammatory disorder characterized by the ectopic growth of endometrial-like tissue, leading to pelvic pain and infertility. Although cepharanthine has well-established anti-inflammatory properties, its therapeutic potential and …
To establish a standardized and reproducible rat model of endometriosis by refining the classic Vivian technique, with the aim of minimizing methodological variability and replicating key features of human disease.
In modern society, the progression of ovarian aging in women has accelerated, and the incidence of infertility has increased markedly with a distinct younger-onset trend. Exploring the etiology and pathogenesis …
Background/Objectives: Endometriosis is a chronic estrogen-dependent disease with a complex and incompletely understood etiology. Environmental exposure to toxic elements, including cadmium, lead, mercury, and arsenic, may contribute to its development …
Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a well-established stem cell marker in multiple epithelial tissues. However, its spatial distribution and biological relevance in normal and pathological human endometrium remain …
Brazil recently implemented a national menstrual health program within its public health system (Sistema Único de Saúde [SUS]), representing a significant policy shift toward recognizing menstrual dignity as a public …
Bacterial vaginosis (BV) is a common dysbiotic condition associated with adverse pregnancy outcomes, including preterm delivery, and its diagnosis remains challenging due to limitations of conventional methods and the lack …
Chronic pelvic pain (CPP) is a prevalent, disabling syndrome encompassing overlapping disorders such as endometriosis/adenomyosis, bladder pain syndrome/interstitial cystitis, irritable bowel syndrome, vulvodynia, and myofascial pain syndrome. Despite distinct clinical …