The rate of implantation of endometrial tissue onto the appendix varies greatly within the literature with appendiceal intussusception being a rare clinical presentation in this small subset of patients. Here …
Endometriosis-associated infertility is a complex condition in which the presence of endometrial-like tissue disrupts implantation and early pregnancy. Epigenetic regulators are critical for implantation and decidualization, yet their contribution to …
Extrapelvic endometriosis can be associated with significant morbidity. Diagnosis is often delayed due to atypical and nonspecific symptoms, as well as the rarity of endometriosis implants in most extrapelvic sites. …
Endometriosis and endometrial cancer are distinct gynecological conditions that share overlapping biological mechanisms with implications for clinical management. Endometriosis is a chronic, benign disorder characterized by the ectopic implantation of …
Precise staging of endometriosis remains a clinical challenge, as current diagnosis depends almost entirely on laparoscopic visualization-an invasive procedure marked by considerable inter-observer disagreement and diagnostic delays. Existing non-invasive approaches, …
The Colony-Stimulating Factor 3 Receptor (CSF3R), the receptor for granulocyte colony-stimulating factor (G-CSF), has expanded from a hematopoietic regulator to a multifunctional signalling molecule with significant relevance in gynaecological biology. …
Per- and polyfluoroalkyl substances (PFAS) accumulate in reproductive tissues, yet most studies rely on serum measurements. It remains unclear whether serum concentrations adequately reflect levels in target tissues. We evaluated …
The endometrium is a highly dynamic and complex tissue lining the uterus, playing a central role in reproductive health. Despite its importance, the pathogenesis of many benign endometrial disorders remains …
The perception that hormonal contraception causes weight gain is a general belief that frequently hinders the initiation and continuation of effective family planning. This narrative review analyses data from Cochrane …
Endometriosis is an estrogen-dependent inflammatory disorder frequently associated with infertility and characterized by progesterone resistance and impaired endometrial receptivity. While ectopic lesions define the disease, accumulating evidence indicates that molecular …