Endometriosis is associated with nociceptive pain, as well as peripheral and central sensitization. Evidence-based treatment suggestions for controlling endometriosis should be based on the convergence of the best scientific evidence, …
Trigeminal nerve injury can lead to chronic and difficult-to-treat orofacial neuropathic pain. Here, we uncover a key role for the cation channel TRPM3 in the chronic constriction injury of the …
Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form …
Pain in endometriosis involves not only nociceptive but also neuropathic and neurogenic components, reflecting its complex nature. Histamine, a biogenic amine, has emerged as a critical mediator connecting inflammation and …
Background/Objectives: The assessment of endometriosis (EMS)-associated pain is important, but only very few studies address the potential use of questionnaires for non-invasive prediction of the disease. Methods: In a prospective …
Endometriosis is a chronic, inflammatory disease with considerable symptom load in affected female patients. Cyclic pain (associated with menstruation) dominates in most patients, but few patients suffer from persistent non-cyclic …
To demonstrate a standardized and reproducible technique utilizing intraoperative neurophysiological monitoring (IONM) with real-time nerve mapping to improve the safety of deep infiltrating endometriosis surgery and facilitate the preservation of …
Endometriosis is a chronic, hormone-dependent disease affecting up to 10% of women of reproductive age, often associated with chronic pelvic pain (CPP). Neuropathic pain has been increasingly recognized as a …
As a gynecological disease, endometriosis is a disease in which pain and inflammation are important parts. Endometriosis is a chronic, estrogen-related situation with a multifactorial etiology that remains incompletely understood. …
Chronic pelvic pain is a severe condition affecting patients with endometriosis. Treatment options range from physical therapy, medical management, to surgical resection. However, some patients continue to have severe pain …