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Systems-level actions of luteolin in female reproductive disorders: from molecular mechanisms to clinical translation.

Female reproductive disorders represent a major global health challenge. Despite their clinical heterogeneity, these conditions share core pathological mechanisms including oxidative stress, chronic inflammation, hormonal imbalance, metabolic dysfunction, extracellular matrix …

Published: Feb. 25, 2026, midnight
A pre-post prospective study on the use of Transcutaneous Electrical Nerve Stimulation (TENS) unit in the management of endometriosis pain.

Primary aim is to identify the impact of Transcutaneous Electrical Nerve Stimulator (TENS) use on endometriosis pain based on daily self-reported Visual Analogue Scores (VAS) during pain flares. Secondary aims …

Published: Feb. 24, 2026, midnight
Primary dysmenorrhea in adolescents.

Dysmenorrhea is among the most common gynecological complaints in adolescents. Its diagnosis depends on the exclusion of other underlying pathologies, with the patient's history playing a crucial role. Initial therapy …

Published: Feb. 24, 2026, midnight
The role of gut microbiota in modulating estrogen in the inflammatory milieu of endometriosis: A molecular and pathophysiological perspective.

Endometriosis is a prevalent estrogen-dependent chronic inflammatory condition that affects millions of women of reproductive age worldwide. It is characterized by the growth of endometrial tissue outside the uterine cavity, …

Published: Feb. 24, 2026, midnight
Pelvic Congestion Syndrome: The Gynecological Perspective.

Background/Objectives: Chronic pelvic pain (CPP) is defined as pelvic pain lasting longer than six months and is a common yet often overlooked condition, affecting over 40% of women worldwide and …

Published: Feb. 22, 2026, midnight
Primary Amenorrhea With Bilateral Endometriomas in a Teenager Girl With Cervical Hypoplasia and Vaginal Agenesis.

A rare case of primary amenorrhea caused by cervical hypoplasia and vaginal agenesis highlights the critical need for early diagnosis and timely surgical intervention to prevent severe complications such as …

Published: Feb. 19, 2026, midnight
Central sensitization in women with endometriosis: a cross-sectional study.

Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form …

Published: Feb. 17, 2026, midnight
Fertility after endometriosis surgery: a systematic review and meta-analysis comparison of primary versus multiple surgical interventions.

Symptoms of endometriosis are often incompletely managed and recurrent surgeries are commonplace. The impact of re-operation on fertility remains unclear. This systematic review compares fertility outcomes in patients who underwent …

Published: Feb. 15, 2026, midnight
Diagnosis and Therapy of Endometriosis. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/045, April 2025).

Objective The objective of this revised official guideline, published by the German Society for Gynecology and Obstetrics (DGGG) and coordinated in the joint guidelines program of the DGGG, the Austrian …

Published: Feb. 11, 2026, midnight
Amygdalin inhibits 17β-estradiol-induced mesenchymal transition through TGF- β/Smad signaling in normal and endometriotic endometrial epithelial cells.

Endometriosis is a common gynecological disorder characterized by chronic pelvic pain, infertility, and systemic symptoms, with currently limited treatment options. Amygdalin, a cyanogenic glycoside derived from bitter apricot kernels, has …

Published: Feb. 11, 2026, midnight
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