Pain is a defining symptom of endometriosis reducing quality of life and increasing the risk of psychological disorders. We conducted an open-label, randomized, controlled trial to investigate whether structured coaching …
Intestinal endometriosis is a benign gynecological condition that frequently involves the rectosigmoid colon. Its synchronous occurrence with colorectal cancer is exceptionally rare and diagnostically challenging, particularly when mimicking a second …
Ovarian endometriosis is a chronic inflammatory disease characterized by extensive tissue remodeling and fibrosis, which significantly impacts female reproductive health. This study demonstrates that ectopic endometrium (Ect) in patients with …
Background/Objectives: Primary renal endometriosis with extrapelvic locations of endometriosis lesions is deemed extremely rare. Therefore, the aim of this review was to assess the current literature on renal endometriosis, encompassing …
Human papillomavirus (HPV) infection is a necessary but insufficient cause of cervical cancer (CC) and reflects a long-standing host-virus equilibrium shaped by immune control, viral persistence, and latency. The transition …
Oocyte quality is the primary determinant of success in assisted reproductive technologies (ART), and mitochondrial dysfunction is increasingly recognized as a central mediator of poor oocyte competence across advanced maternal …
Endometriosis (EMS) is an estrogen-dependent inflammatory disease affecting 10% of reproductive-age women, with up to 50% experiencing infertility. As primary care providers (PCPs) are often the first point of care, …
Endometriosis is a chronic, estrogen-dependent inflammatory disorder affecting approximately 10% of women of reproductive age. Retrograde menstruation is widely accepted as a primary mechanism for ectopic endometrial seeding; however, only …
Background and Objectives: Superficial peritoneal endometriosis (SPE) remains one of the most difficult endometriosis phenotypes to diagnose non-invasively, because lesions are frequently small, multifocal, and poorly detectable using conventional imaging. …
Karyopharm’s selinexor misses primary endpoint in Phase 3 endometrial cancer trial The Clinical Trial Vanguard