Latest Articles

Three- and Four-Dimensional Pelvic Floor Ultrasound in Chronic Pelvic Pain: Evidence, Technical Considerations, and a Proposed Framework.

Chronic pelvic pain (CPP) is a heterogeneous condition in which visceral, musculoskeletal, neuropathic, and pain-processing contributors often overlap. Pelvic floor ultrasound can depict morphology and movement, but its CPP-specific evidence …

Long non-coding RNAs in female infertility: Advancing from molecular insights to clinical relevance.

A broad range of genetic and epigenetic factors contributes to female infertility, a substantial proportion of which is related to ovulatory disorders. Any factor that disrupts the normal function of …

2-Deoxyglucose Dendrimer-Enabled Niclosamide Delivery to FRβ-Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia.

Endometriosis (EuE) is a chronic, incurable disease. Due to limited efficacy, high recurrence rates, and serious side effects of current treatments, development of new, targeted, nonhormonal therapies is urgently needed. …

Research Progress of Autophagy and Ferroptosis in Endometriosis.

Endometriosis （EMs） is a common and refractory disease in clinical practice.It has the pathological characteristics of adhesion and invasion，while the pathogenesis remains unclear.In recent years，studies have found that autophagy and …

Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care.

Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances …

Targeted interleukin 8 (IL-8 or CXCL8) for treating endometriosis.

From polygenic risk to functional genomics: a framework for precision gynecological disease modeling.

Gynecological conditions including endometriosis, polyendocrine metabolic ovarian syndrome and malignancies cause widespread chronic morbidity and infertility, yet translating genetic discoveries into biological mechanisms remains challenging. We propose a framework integrating …

The Phendo Project: How FemTech Is Advancing Endometriosis Research and Women's Health.

FemTech continues to evolve and advance despite persistent research and funding gaps. In this News and Perspectives article, JMIR Correspondent Jenny Castillo Cato reports on an innovative, cross-disciplinary research project …

Targeting Imaging Modality in the Diagnosis of Endometriosis: 68Ga-FAPI-04 PET/CT.

Endometriosis is a chronic condition in reproductive-age women, and diagnosis can be delayed for 4-11 years due to nonspecific symptoms and limited imaging. This underscores the need for new methods …

Study on the role of miR-433-3p in the occurrence and development of endometriosis.

This study aims to characterize the expression pattern and biological functions of miR-433-3p in endometriosis. Eutopic and ectopic endometrial tissues were collected from endometriosis patients, and the expression level of …