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High inhibition ratio and transformation index of 2 mg dienogest: further evidence for its use in endometriosis treatment.

Endometriosis is a common, chronic disease with a high burden for women, characterised by the implantation of endometrial cells outside the uterus. Many different treatments have been proposed for this …

Published: Dec. 2, 2025, midnight
Natural bioactive compounds and herbal medicines targeting common signaling pathways in endometriosis: mechanisms and therapeutic implications.

For a very long time, herbal treatments have served as remedies for various humans and animals. Natural compounds typically have multiple pharmacological actions because they interact with various biological targets. …

Published: Dec. 2, 2025, midnight
The role of pharmacotherapy in the treatment of endometriosis: an update.

Endometriosis is a chronic inflammatory condition affecting ~10% of reproductive-age individuals and contributing significantly to infertility, pain, and reduced quality of life. Since our 2020 review, new pharmacologic strategies, updated …

Published: Dec. 2, 2025, midnight
The value of 4-dimensional hysterosalpingo-contrast sonography in predicting the possibility of spontaneous conception in infertile women.

Some infertile women can undergo spontaneous conception after 4-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy). However, advised period of expectant management after HyCoSy for different tubal patency was rarely recorded. This study aimed …

Published: Dec. 1, 2025, midnight
Patients' knowledge, attitudes, and practices concerning endometriosis and its long-term management.

Endometriosis, affecting 10-15% of women, causes pain and infertility. Current treatments have limitations. This study aimed to investigate patients' knowledge, attitude, and practice (KAP) concerning endometriosis and its long-term management.

Published: Nov. 28, 2025, midnight
The Financial Toxicity of Endometriosis: Unseen Costs and Policy Gaps.

Endometriosis affects 1 in 10 Canadians, yet its financial toxicity remains poorly understood. While universal healthcare covers physician and hospital services, patients face substantial out-of-pocket costs for medications, complementary therapies, …

Published: Nov. 28, 2025, midnight
Patient-derived epithelial cell organoids mimic the phenotypic complexity of endometriosis subtypes.

Can patient-derived organoid models be reliably established from diverse surgical phenotypes of endometriosis, and how do clinical factors such as hormonal treatment affect their growth success and morphology?

Published: Nov. 27, 2025, midnight
Evaluation of the feasibility and contribution of multi-faceted ultrasound in the operating room to facilitate the shaving technique in the treatment of rectal endometriosis.

To evaluate the feasibility and potential contribution of preoperative and intraoperative ultrasound in rectal shaving, to support surgical decision-making and achieve optimal lesion excision.

Published: Nov. 27, 2025, midnight
Personalized Vaginal Drug Delivery through 3D Printing: Techniques, Challenges, and Future Perspectives.

Vaginal disorders in reproductive‑age women, including bacterial vaginosis (affecting 23-29%), endometriosis, etc., are increasing alarmingly day by day worldwide. Vaginal drug delivery (VDD) has garnered notable attention in the pharmaceutical …

Published: Nov. 26, 2025, midnight
Appendiceal endometriosis: an uncommon manifestation of deep infiltrating endometriosis.

Appendiceal endometriosis is a rare cause of acute appendicitis, accounting for approximately 1% of cases.This report describes a case of a female patient presenting with right iliac fossa pain and …

Published: Nov. 26, 2025, midnight
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