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CXCL12 promotes EMT-mediated malignant transformation of endometriosis-associated ovarian cancer via PI3K/Akt signaling: An integrated transcriptomic and clinical study.

Endometriosis-associated ovarian cancer (EAOC) is a distinct form of epithelial ovarian cancer that arises from the malignant transformation of benign endometriotic lesions. While epithelial-mesenchymal transition (EMT) is acknowledged as a …

Published: Jan. 16, 2026, midnight
Endometriosis as a Systemic and Complex Disease: Toward Phenotype-Based Classification and Personalized Therapy.

Endometriosis is traditionally conceptualized as a pelvic lesion-centered disease; however, mounting evidence indicates it is a chronic, systemic, and multifactorial inflammatory disorder. This review examines the molecular dialog between ectopic …

Published: Jan. 16, 2026, midnight
Correlates of body image in individuals with endometriosis: The role of body compassion and endometriosis-related symptoms.

Knowledge pertaining to the interplay between body image, body compassion, and endometriosis-related symptoms is limited. The current study aimed to elucidate the relationships between body compassion, body image, and endometriosis-related …

Published: Jan. 15, 2026, midnight
A duo of redox-sensitive pore-loop cysteines controls the activity of the neural ion channel TRPM3.

Transient Receptor Potential Melastatin 3 (TRPM3) is a non-selective, Ca2+-permeable ion channel that plays a pivotal role in peripheral thermosensation and nociception. Moreover, gain-of-function variants in TRPM3 underlie a spectrum …

Published: Jan. 14, 2026, midnight
In silico evaluation of procyanidin as a potential ESR1 inhibitor: docking and MD insights in uterine fibroids and endometriosis.

These are two of the most common gynecologic diseases, affecting 15% to 80% of women of childbearing age diseases. The existing treatments, such as hormonal drugs and selective estrogen receptor …

Published: Jan. 14, 2026, midnight
Plasma extracellular vesicle modulate immune cell transcriptional responses following acute myocardial infarction.

Plasma extracellular vesicles (EVs) increase during acute myocardial infarction (MI), correlate with myocardial injury, and mobilize immune cells from the spleen to the circulation. These cells are transcriptionally activated even …

Published: Jan. 14, 2026, midnight
Development of medical freezing measures in women during the last decade from 2014 to 2023: registry data of the tri-national network FertiPROTEKT.

To what extent have fertility preservation interventions evolved between 2014 and 2023, and what factors have influenced changes in their utilization and prevalence?

Published: Jan. 13, 2026, midnight
Burden analysis of uterine fibroids and endometriosis in reproductive-age women globally, in China, India, and the United States, 1990-2021.

Uterine fibroids and endometriosis are common benign gynecological diseases affecting the health of women of childbearing age, characterized by high incidence and recurrence rates. Despite the increasing global emphasis on …

Published: Jan. 13, 2026, midnight
Experiences of women with endometriosis & their partners in India: Findings from a qualitative study.

Background & objectives Endometriosis, a chronic inflammatory condition, affects approximately 10 per cent of reproductive-age women in India. This study aimed to explore the experiences of women with endometriosis and …

Published: Jan. 12, 2026, midnight
Integrating IVF and Surgical Management in Endometriosis-Associated Infertility: A Review.

Endometriosis is a chronic, debilitating condition characterized by heterogenous clinical manifestations. It has a prevalence of 5-10% in women of reproductive age, and 30-50% of individuals with endometriosis are affected …

Published: Jan. 12, 2026, midnight
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