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Perturbations of the endometrial immune microenvironment in endometriosis and adenomyosis: their impact on reproduction and pregnancy.

The impact of endometriosis and adenomyosis on reproduction and pregnancy is significant, with both conditions linked to increased rates of infertility, poor ovarian function in women with endometriosis, and elevated …

Published: Feb. 18, 2025, midnight
Gastrointestinal function outcomes following radical and conservative colorectal surgery for deep endometriosis: A systematic review and meta-analysis.

Patients who have undergone colorectal surgery for symptomatic deep endometriosis may still encounter persistent or worsening digestive complaints. The aim of the present work was to analyze gastrointestinal function outcomes …

Published: Feb. 17, 2025, midnight
Informing the Design of Individualized Self-Management Regimens from the Human, Data, and Machine Learning Perspectives.

Intelligent systems for self-management can help patients and improve quality of life. However, designing AI-based systems is challenging because designers need to account not only for user needs, but also …

Published: Feb. 17, 2025, midnight
The impact of surgeon speciality on surgical outcomes following colorectal resection for endometriosis.

An estimated 5%-25% of women with endometriosis have colorectal involvement. Colorectal resection is the most suitable surgical management for cases with large bowel infiltration. However, this method is also associated …

Published: Feb. 15, 2025, 12:15 a.m.
The integral roles of the TGFβ signaling pathway in uterine function and disease.

The uterus is a complex organ that requires precise signaling networks to mediate functions necessary for homeostasis and reproductive processes. The transforming growth factor β (TGFβ) superfamily regulates integral signaling …

Published: Feb. 14, 2025, midnight
Endometriosis and adenomyosis research priorities in India and Sri Lanka: a call for regional collaboration.

Endometriosis and adenomyosis are major gynaecological conditions affecting women of reproductive age-group, particularly in low- and middle-income countries. This Health Policy outlined research priorities for India and Sri Lanka, derived …

Published: Feb. 14, 2025, midnight
Causal Links Between Brain Functional Networks and Endometriosis: A Large-Scale Genetic-Driven Observational Study.

Endometriosis is a chronic gynecological disorder that significantly impacts women of reproductive age. Recent evidence suggests a bidirectional link between endometriosis and brain functional networks, though the causal mechanisms remain …

Published: Feb. 11, 2025, midnight
Efficacy and Safety of Chinese Patent Medicines Combined with Conventional Therapies for Endometriosis: A Systematic Review and Bayesian Network Meta-Analysis.

Conventional hormonal treatments for endometriosis (EMs) are often associated with significant side effects. In recent years, many clinical trials and studies have highlighted the remarkable efficacy of Chinese patent medicines …

Published: Feb. 8, 2025, midnight
BCL6 (B-cell lymphoma 6) expression in adenomyosis, leiomyomas and normal myometrium.

Adenomyosis and leiomyomas are common benign uterine disorders characterized by abnormal cellular proliferation. The BCL6 protein, a transcriptional repressor implicated in cell proliferation and oncogenesis, has been linked to the …

Published: Feb. 4, 2025, midnight
Eligibility criteria for the use menopausal hormone therapy (MHT) in women with medical conditions (II): Endometriosis, neurological and autoimmune diseases.

This project developed eligibility criteria for menopausal hormone therapy in patients with medical conditions beyond those published in a previous report. A new consortium of scientific societies coordinated by the …

Published: Jan. 30, 2025, midnight
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