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Effects of Exosomes Derived From Eutopic Endometrial Cells in Endometriosis and the Discovery of Related Serum miRNA Biomarkers for Endometriosis.

Exosomes are secreted by most cell types and reflect the internal state of their cells of origin, playing crucial roles in the progression of various pathological conditions. Endometriosis is a …

Published: Sept. 9, 2025, midnight
Risk of Abortion and Ectopic Pregnancy in Women with a History of Polycystic Ovary Syndrome: A Nationwide Population-Based Cohort Study.

Objectives: The purpose of this retrospective cohort study was to ascertain the risk of abortion, ectopic pregnancy and hydatidiform mole development in women with polycystic ovary syndrome (PCOS) using data …

Published: Sept. 7, 2025, midnight
Correlation between the AAGL 2021 classification and the occurrence of perioperative complications in endometriosis surgery.

The AAGL 2021 classification assesses intraoperative surgical complexity using a four-stage scale based on lesion size and location. Despite its potential utility, no data currently assess its correlation with perioperative …

Published: Sept. 6, 2025, midnight
MIG-6 Plays a Critical Role as a PGR Mediator in Maintaining Epithelial and Stromal Cells for Uterine Receptivity.

Ovarian steroid hormones-estrogen and progesterone-play a central role in regulating epithelial-stromal interactions in the uterus. These interactions are critical for uterine function, including endometrial receptivity, implantation, and decidualization. These interactions …

Published: Sept. 5, 2025, midnight
Chemokines and Their Association With Symptom Severity in Women With Endometriosis.

Various chemokines have been linked to endometriosis. Notably, chemokines such as CCL2, CXCL8, and CXCL1 have also been shown to promote nociception. In this study, we investigated whether increased serum …

Published: Sept. 5, 2025, midnight
Dysfunction of natural killer cells promotes immune escape and disease progression in endometriosis.

Endometriosis (EMs) is a chronic inflammatory disorder characterized by dysregulated innate immunity, particularly impaired cytotoxic function of natural killer (NK) cells. As pivotal effectors of the innate immune response, NK …

Published: Sept. 5, 2025, midnight
Meet Juan Gnecco, a professor working to end endometriosis. - The Tufts Daily

Meet Juan Gnecco, a professor working to end endometriosis. The Tufts Daily

Published: Sept. 4, 2025, 4:30 a.m.
Polychlorinated biphenyl Endocrine Disruptor Alters Estrogen Receptor beta-Mediated Epigenetic Regulation, Promoting Endometriosis.

Background Endometriosis is a pathological condition characterized by the ectopic proliferation of endometrial cells, resulting in chronic pelvic pain and infertility. Exposure to endocrine-disrupting chemicals (EDCs) has been implicated in …

Published: Sept. 4, 2025, midnight
Assessment of the Impact of Chronic Pain on the Prevalence of Depressive Disorders in Patients with Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory and immunological disease, with chronic pain being its predominant clinical manifestation. This condition significantly impairs quality of life and is frequently associated with depressive …

Published: Sept. 2, 2025, midnight
Differential life cycle toxic effects and molecular mechanisms of Di(2-ethylhexyl) phthalate (DEHP) exposure on the female reproductive system.

Di(2-ethylhexyl) phthalate (DEHP), the most prevalent plasticizer worldwide, can enter the human body via various exposure pathways, including ingestion, inhalation, skin contact, and medical applications. It has been observed to …

Published: Aug. 31, 2025, midnight
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