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Zearalenone promotes endometrial cancer cell migration and invasion via activation of estrogen receptor-mediated Rho/ROCK/PMLC signaling pathway.

Zearalenone (ZEA), has emerged as a potential endocrine-disrupting chemical (EDC). Previous results show ZEA effects on endometrial stromal cell apoptosis, migration, and growth of endometriosis. Despite the reported presence of …

Published: Sept. 19, 2024, midnight
The role of progesterone and estrogen receptors in treatment choice after endometriosis surgery: A cross-sectional study.

The lack of improvement in some endometriotic people's pain after surgery even while using hormone treatment may suggest an inappropriate response to routine hormonal therapies.

Published: Sept. 12, 2024, midnight
The vicious cycle of chronic endometriosis and depression-an immunological and physiological perspective.

Endometriosis is a chronic, estrogen-dependent, proinflammatory disease that can cause various dysfunctions. The main clinical manifestations of endometriosis include chronic pelvic pain and impaired fertility. The disease is characterized by …

Published: Sept. 6, 2024, midnight
M1 macrophages as promising agents for cell therapy of endometriosis.

Endometriosis is a chronic estrogen-dependent disease characterized by the presence of endometrial glands and stroma outside their normal anatomical location. While laparoscopic removal of foci remains the gold standard therapy, …

Published: Aug. 14, 2024, midnight
The rs2046210 Polymorphism Is Associated with Endometriosis Risk and Elevated Estrogen Receptor 1 Expression in the Eutopic Endometrium of Women with the Disease.

In this focused genetic case-control study, we analyzed two functional single-nucleotide variants (SNVs) associated with breast cancer risk (rs2046210, rs9383590) and one risk SNV for an implantation defect and infertility …

Published: July 25, 2024, midnight
The spectrum of oestrogen receptor expression in endometrial carcinomas of no specific molecular profile - Wiley Online Library

The spectrum of oestrogen receptor expression in endometrial carcinomas of no specific molecular profile Wiley Online Library

Published: June 18, 2024, 7 a.m.
Estrogen-Only Therapy for Menopausal Symptoms Increases Ovarian Cancer Risk - Medpage Today

Estrogen-Only Therapy for Menopausal Symptoms Increases Ovarian Cancer Risk Medpage Today

Published: May 24, 2024, 7 a.m.
Oestrogen promotes the progression of adenomyosis by inhibiting CITED2 through miR-145.

Is the microRNA miR-145 involved in adenomyosis, and by what mechanisms does it affect disease development and is itself regulated?

Published: May 12, 2024, midnight
The prognostic value of MEK pathway–associated estrogen receptor signaling activity for female cancers - Nature.com

The prognostic value of MEK pathway–associated estrogen receptor signaling activity for female cancers Nature.com

Published: April 6, 2024, 7 a.m.
Melatonin: Current evidence on protective and therapeutic roles in gynecological diseases.

Melatonin, a potent antioxidant and free radical scavenger, has been demonstrated to be effective in gynecological conditions and female reproductive cancers. This review consolidates the accumulating evidence on melatonin's multifaceted …

Published: March 11, 2024, midnight
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