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LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker.

Long interspersed element 1 (LINE-1) retrotransposons are repetitive sequences that can move within the genome by an autonomous mechanism. To limit their mutagenic potential, benign cells restrict LINE-1 expression through …

Published: March 6, 2025, midnight
The Role of Mast Cells in the Development and Advancement of Endometriosis.

Endometriosis is a medical condition identified by the presence of endometrium-like tissue outside the uterus. This condition is known to result in symptoms such as frequent pelvic pain, infertility, and …

Published: March 4, 2025, 12:17 a.m.
Vitamin D in Reproductive Health Disorders: A Narrative Review Focusing on Infertility, Endometriosis, and Polycystic Ovarian Syndrome.

Vitamin D (VD) is a fat-soluble steroid hormone with essential physiological functions beyond calcium and bone metabolism. In recent years, its role in women's reproductive health has gained attention, influencing …

Published: March 3, 2025, midnight
miRNA-1229-5p promotes migration and invasion and suppresses apoptosis of endometrial cells via the STMN1/p38 MAPK axis in endometriosis.

Emerging evidence suggests that aberrantly expressed microRNAs (miRNAs) participate in endometriosis pathogenesis. miR-1229-5p participates in the pathogenesis of several disease, but its precise role and mechanism in endometriosis is unclear.

Published: March 2, 2025, midnight
Unveiling the connection: asthma and endometriosis - a comprehensive systematic review and meta-analysis.

Asthma and endometriosis are two prevalent chronic conditions that affect a significant portion of the population. Both conditions have been linked to inflammatory processes and immune dysregulation, suggesting the possibility …

Published: March 1, 2025, midnight
A systematic review and meta-analysis of advanced oxidative protein products levels (AOPP) levels in endometriosis: association with disease stage and clinical implications.

Endometriosis is a common cause of chronic pelvic pain and lacks precise pathophysiological mechanisms. Advanced oxidation protein products (AOPPs), markers of oxidative stress and inflammation, are implicated in pain-related diseases …

Published: Feb. 28, 2025, midnight
Endometriosis and Cytoskeletal Remodeling: The Functional Role of Actin-Binding Proteins.

Endometriosis is a chronic, estrogen-dependent gynecological disorder characterized by the presence of endometrial-like tissue outside the uterine cavity. Despite its prevalence and significant impact on women's health, the underlying mechanisms …

Published: Feb. 28, 2025, midnight
Fertility preservation in women with endometriosis.

Endometriosis is a chronic disease that can compromise fertility in up to 30-50% of affected patients, and it is estimated that patients affected by endometriosis represent about 10% of patients …

Published: Feb. 28, 2025, midnight
The Role of Adenogenesis Factors in the Pathogenesis of Endometriosis.

Endometriosis is a pathological condition characterized by the presence of the endometrial tissue, outside the uterine cavity. It affects nearly 10% of women of reproductive age and is responsible for …

Published: Feb. 27, 2025, midnight
Causal Effect Between Natural Hair Color and Endometriosis in a European Population: A Two-Sample Mendelian Randomization.

Previous observational studies have suggested an association between natural hair color and the risk of endometriosis; however, the causal relationship remains unclear. Here, we conducted a two-sample Mendelian randomization (MR) …

Published: Feb. 25, 2025, midnight
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