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From Gynecological Endocrine Disorders to Cardiovascular Risk: Insights from Rat Models.

Gynecological endocrine disorders, including polycystic ovary syndrome (PCOS), endometriosis as well as primary ovarian insufficiency (POI)/premature ovarian failure (POF), significantly impact women's reproductive health and overall well-being. While these conditions …

Beyond the scar: a retrospective analysis of a rare subtype of abdominal wall endometriosis with muscle fascia invasion and its surgical implications.

Fluorescence-Guided Bladder and Ureter Visualization in Benign Robotic Gynecologic Surgery: A Series of Five Cases.

Indocyanine green (ICG) near-infrared fluorescence imaging is well established in gynecologic oncology, but its role in benign minimally invasive surgery is still limited and not standardized. Increasing cesarean section and …

Impact of Physical Activity on Ovarian Response: A Prospective Study Among In Vitro Fertilization Patients.

Introduction Scientific evidence has shown that regular physical activity (PA) is beneficial to health. However, no consensus has been reached on the association between PA and the success rates of …

Personalized Estimation of Fatigue in Endometriosis Using Wrist-Worn Actigraphy Data and Hierarchical Bayesian Modeling.

Endometriosis is a common chronic condition associated with debilitating pain and fatigue. Wearable technology has the potential to improve symptom monitoring in endometriosis where symptom severity has been traditionally evaluated …

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review).

Endometriosis is a complex, chronic inflammatory gynecological disorder with estrogen‑dependent characteristics that severely impairs the quality of life of women and potentially leads to infertility. However, its pathogenesis remains poorly …

Exome-Based Identification of Candidate Genes in Sporadic Adenomyosis Cases.

Background: Adenomyosis is a benign uterine disorder defined by the invagination of ectopic endometrial-like tissue into the myometrium, causing heavy menstrual bleeding and pain. While its pathogenesis remains unclear, shared-symptomology …

ZMIZ1 and estrogen receptor α form an essential partnership in endometrial biology.

Estrogen receptor α (ESR1) is a pivotal regulator of endometrial homeostasis and reproductive function, yet the coregulators that fine tune its transcriptional activity remain incompletely defined. In this issue of …

Transcriptional coregulator ZMIZ1 modulates estrogen responses that are essential for healthy endometrial function.

Estrogen is a critical regulator of endometrial health. Aberrant estrogen stimulation can result in infertility, endometrial cancer, and endometriosis. Here, we identified Zinc Finger MIZ-Type Containing 1 (Zmiz1) as a …

Endometriosis in Carriers of a Pathogenic Variant in BRCA1 or BRCA2: A Descriptive Analysis of a Large Multicentral BRCA Carrier Cohort.

Background: Endometriosis affects an estimated 10% of reproductive-aged women and is associated with increased ovarian cancer risk. While BRCA1/2 mutations are established risk factors for ovarian cancer, their association with …