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Cross-Tissue Regulatory Network Analyses Reveal Novel Susceptibility Genes and Potential Mechanisms for Endometriosis.

Endometriosis (EMT) is a common gynecological disease with a strong genetic component, while its precise etiology remains elusive. This study aims to integrate transcriptome-wide association study (TWAS), Mendelian randomization (MR), …

Published: Oct. 26, 2024, midnight
Association of psychosocial factors at work with fertility and menstrual disorders: A systematic review.

This systematic review aimed to assess the association between psychosocial factors in the workplace and menstrual abnormalities or fertility, focusing on literature implementing a prospective cohort design.

Published: Oct. 19, 2024, midnight
Current developments in endometriosis-associated pain.

Endometriosis-associated pain is burdensome to both the individual and wider society. However, current treatment leaves many with persisting pain. Here, we highlight how recent work considering endometriosis in the context …

Published: Oct. 18, 2024, midnight
Understanding diagnostic delay for endometriosis: A scoping review using the social-ecological framework.

Diagnostic delay for endometriosis is a well-established phenomenon. Despite this, little is known about where in the health care system these delays occur or why they occur. Our review is …

Published: Oct. 17, 2024, midnight
The mechanism of wen jing tang in the treatment of endometriosis: Insights from network pharmacology and experimental validation.

Endometriosis (EM) is a hormone-dependent condition marked by progressively severe secondary dysmenorrhea, significantly impacting patients' quality of life and overall health. Wen Jing Tang (WJT), a traditional Chinese medicinal formulation …

Published: Oct. 17, 2024, midnight
Cross-disciplinary working between gynaecologists and mental healthcare professionals: a mixed-methods systematic review protocol.

Reproductive hormone transitions (menstrual cycle, post partum and menopause) can trigger mental disorders in a subset of women. Gynaecological diseases, such as endometriosis and polycystic ovary syndrome, can also elevate …

Published: Oct. 16, 2024, midnight
[Guideline for the diagnosis and treatment of endometriosis (Third edition)].

This is the third edition of guideline for the diagnosis and treatment of endometriosis in China. The second edition was published six years ago in 2015. It has been an …

Published: Oct. 14, 2024, 1:26 p.m.
Network-based pharmacology and experimental validation to explore the mechanism of action of the Jiawei Pentongling formula for the treatment of endometriosis-related pain.

To investigate the effects and mechanisms of the Jiawei Pentongling formula (, JWPTL) in treating endometriosis-related pain using network pharmacology study and experimental validation.

Published: Oct. 13, 2024, 4:36 p.m.
Immune infiltration related circular RNA, circGLIS2, facilitated progression of endometriosis through miR-4731-5p/IL-1β axis.

Aberrantly expressed circRNAs affect various anti-tumour immune responses and immune cell regulation. However, the exact function of circGLIS2 on the pathogenesis of EMs remains unclear. In this study, we found …

Published: Oct. 4, 2024, midnight
Carnitine traffic and human fertility.

Carnitine is a vital molecule in human metabolism, prominently involved in fatty acid β-oxidation within mitochondria. Predominantly sourced from dietary intake, carnitine also derives from endogenous synthesis. This review delves …

Published: Oct. 3, 2024, midnight
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