Latest Articles

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Could the estrobolome have a role in endometriosis pathogenesis and infertility? A systematic review.

Endometriosis is a chronic, estrogen-dependent condition affecting 10% of reproductive-aged women, often associated with infertility and chronic pelvic pain. Recent evidence suggests that gut microbiota dysbiosis and alterations in the …

Published: Dec. 18, 2025, midnight
Expression of Concern: Uterine leiomyoma is associated with the risk of developing endometriosis: A nationwide cohort study involving 156,195 women.

Published: Dec. 18, 2025, midnight
A pilot study of cervicovaginal microbiome patterns associated with embryo implantation outcomes in endometriosis-associated infertility.

The cervicovaginal microbiome-spanning from the vagina to endometrium-remains undercharacterized in endometriosis-associated infertility. Objective: To determine whether combined vaginal and cervical microbial profiles predict frozen embryo transfer (FET) outcomes.

Published: Dec. 18, 2025, midnight
Endometriosis as an immune-mediated disease: pathogenetic mechanisms and therapeutic strategies.

Endometriosis, which affects approximately 10% of women of reproductive age, is a complex inflammatory disease with significant immune system disturbances caused by an inadequate immune response to retrograde menstruation and …

Published: Dec. 18, 2025, midnight
Clinical Effectiveness and Cost-Effectiveness of Misoprostol in Comparison to Dilatation and Curettage for Treatment of First-Trimester Missed Abortion (Gestational Age ≤ 14 Weeks) in Iran.

The development of prostaglandins and antiprogestins revolutionized medical abortion by providing effective nonsurgical options for terminating pregnancy. Although both strategies are accepted in practice, variations in clinical efficacy, patient experiences, …

Published: Dec. 17, 2025, midnight
Borderline ovarian clear cell tumor arising from endometriosis during long-term dienogest therapy: a case report.

Endometriomas, commonly known as ovarian chocolate cysts, are a prevalent condition in women of reproductive age. They are cysts formed by the ectopic growth of endometrial tissue within the ovary, …

Published: Dec. 17, 2025, midnight
Is surgery for endometriomas ever indicated?

Endometriomas can be managed through various approaches, including careful observation, medical suppressive therapy, or surgical intervention. Malignancy is rarely a concern in women of reproductive age, making pain relief and …

Published: Dec. 15, 2025, midnight
Delayed onset of HPV-associated uterine malignancies: seven pathogenetic factors in contrast to cervical cancer.

Human papillomavirus (HPV) is a well-established etiological agent for cervical cancer, yet its contribution to endometrial malignancies remains underrecognized and mechanistically distinct. This paper synthesizes current evidence to explain the …

Published: Dec. 13, 2025, midnight
Systematic review of the literature: estimation of the most common gynecological disorders and associated factors among Kazakhstani adolescents.

Published: Dec. 13, 2025, midnight
Non-Invasive Methods for Early Diagnosis of Endometriosis-A Comprehensive Narrative Literature Review.

Endometriosis is a common gynecological pathology, with an incidence of nearly 10% in patients of reproductive age, and is still underdiagnosed. A thorough and well-spread diagnostic study of endometriosis based …

Published: Dec. 13, 2025, midnight
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