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Transcript profiling and gene regulation of the human pre-implantation embryo: parental effects and impact of ARTs.

Infertility is a growing global challenge, with ARTs significantly improving birth rates for infertile couples. However, ART conceptions are associated with a higher risk of negative obstetrical and perinatal outcomes, …

Published: Sept. 2, 2025, midnight
Endometriosis and menopausal health: An EMAS clinical guide.

Endometriosis is a common gynecological condition, and problems may persist or develop after the menopause. Endometriosis or its treatment in premenopausal women may lead to premature or early menopause. Thus, …

Published: Sept. 2, 2025, midnight
Differential life cycle toxic effects and molecular mechanisms of Di(2-ethylhexyl) phthalate (DEHP) exposure on the female reproductive system.

Di(2-ethylhexyl) phthalate (DEHP), the most prevalent plasticizer worldwide, can enter the human body via various exposure pathways, including ingestion, inhalation, skin contact, and medical applications. It has been observed to …

Published: Aug. 31, 2025, midnight
Large Language Models Reveal Menstruation Experiences and Needs on Social Media.

The gender knowledge gap in medicine, particularly regarding menstruation and disorders such as endometriosis, often results in delayed diagnoses and inadequate care. Many menstruating individuals report dismissal of debilitating symptoms, …

Published: Aug. 27, 2025, 12:01 a.m.
'The Difficulty of Diagnosis Compromises Patient Care for People With Endometriosis': Interview Study With Aotearoa New Zealand General Practitioners.

General practitioners (GPs) are gatekeepers to specialist attention for endometriosis in the public system in Aotearoa New Zealand (Aotearoa-NZ). Their perspective of the endometriosis care landscape in Aotearoa-NZ has not …

Published: Aug. 27, 2025, midnight
Gut Microbiota-Derived Acetate Ameliorates Endometriosis via JAK1/STAT3-Mediated M1 Macrophage Polarisation.

Endometriosis (EMs) is a common inflammatory disorder in women of reproductive age, severely impacting patients' quality of life and fertility. Current hormonal therapies offer limited efficacy, and surgical interventions often …

Published: Aug. 27, 2025, midnight
Reproductive Autonomy and Insurer Denials of Care: The Fine Line Between Oversight and Interference.

AbstractReproductive autonomy is a fundamental ethical principle in healthcare, yet insurance denials of care often undermine patient decision-making. This article examines a case in which a 35-year-old patient with stage …

Published: Aug. 27, 2025, midnight
Nanotechnology strategies for endometrium health: Are we on the right track?

The endometrium is a vital mucosal tissue which undergoes cyclical regeneration, differentiation, and remodeling upon hormonal, cellular, and molecular signaling networks. Dysregulation of these processes can trigger a range of …

Published: Aug. 27, 2025, midnight
Designing and validating a health promotion program for women with endometriosis: a mixed-methods study protocol.

Endometriosis is a benign and chronic gynecological estrogen-dependent disease. Research has shown that endometriosis can affect various dimensions of women's lives. It is recommended that programs be developed to improve …

Published: Aug. 26, 2025, midnight
3D map-guided modeling of functional endometrial tissue using multi-compartment assembloids.

The human endometrium is a dynamic tissue that lines the uterus and undergoes constant remodeling, making it especially susceptible to gynecological diseases like endometriosis and endometrial cancer. The molecular mechanisms …

Published: Aug. 23, 2025, midnight
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