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Tetramethylpyrazine Confers Protection Against Oxidative Stress and NLRP3-Dependent Pyroptosis in Rats with Endometriosis.

Tetramethylpyrazine (TMP) has been confirmed to suppress inflammation in endometriosis (EMs). Herein, this study investigated whether and how TMP affected NLRP3 inflammasomes and oxidative stress in EMs. After establishment of …

Published: Feb. 18, 2025, midnight
Ultrasound of the uterosacral ligaments: A reliability study for diagnosing endometriosis in Australian non-specialised medical imaging and radiology settings.

Uterosacral ligaments (USL) are the most common sites of endometriosis. Transvaginal ultrasound (TVS) demonstrates high diagnostic accuracy for endometriosis of the USLs using standardised technique and characterisations. While high accuracy …

Published: Feb. 18, 2025, midnight
Endometriosis Clinical and Surgical Care During the COVID-19 Pandemic: A Comparison of Virtual-Only Care to Virtual and In-Person Care Combined.

Endometriosis is a chronic and inflammatory condition that affects approximately 10% of the reproductive-age population. During the COVID-19 pandemic, there was a shift towards virtual care for endometriosis. Our aim …

Published: Feb. 18, 2025, midnight
Reproductive tract microbiome dysbiosis associated with gynecological diseases.

Female health and the microbiota of the reproductive tract are closely associated. The research scope on reproductive tract microbiota extends from the vaginal to the upper reproductive tract and from …

Published: Feb. 18, 2025, midnight
Gastrointestinal function outcomes following radical and conservative colorectal surgery for deep endometriosis: A systematic review and meta-analysis.

Patients who have undergone colorectal surgery for symptomatic deep endometriosis may still encounter persistent or worsening digestive complaints. The aim of the present work was to analyze gastrointestinal function outcomes …

Published: Feb. 17, 2025, midnight
A "novel" MRI sequence for improving conspicuity and detection of hemorrhagic foci in pelvic endometriosis: Technical note.

There is a growing need to develop new MRI sequences to identify and characterize hemorrhagic foci within endometriosis lesions. These foci are pivotal, as they represent a significant component of …

Published: Feb. 17, 2025, midnight
Reprogramming peritoneal macrophages with outer membrane vesicle-coated PLGA nanoparticles for endometriosis prevention.

Endometriosis is a chronic inflammatory disease that primarily affects women of reproductive age. The current hormonal treatments are unsuitable for women who wish to conceive, highlighting the need for non-hormonal …

Published: Feb. 17, 2025, midnight
Single-cell dual-omics reveals translational and transcriptional landscapes and regulations in oocytes from ovarian endometriosis patients.

A significant proportion of women in their reproductive years are afflicted by endometriosis. And one of the major contributing factors to infertility linked to ovarian endometriosis is thought to be …

Published: Feb. 17, 2025, midnight
Informing the Design of Individualized Self-Management Regimens from the Human, Data, and Machine Learning Perspectives.

Intelligent systems for self-management can help patients and improve quality of life. However, designing AI-based systems is challenging because designers need to account not only for user needs, but also …

Published: Feb. 17, 2025, midnight
The impact of surgeon speciality on surgical outcomes following colorectal resection for endometriosis.

An estimated 5%-25% of women with endometriosis have colorectal involvement. Colorectal resection is the most suitable surgical management for cases with large bowel infiltration. However, this method is also associated …

Published: Feb. 15, 2025, 12:15 a.m.
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