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Management of Common Benign Gynecologic Diseases in Postmenopausal Women.

This study investigated the impact of menopause on the progression and management of common benign gynecological conditions such as polycystic ovary syndrome, endometriosis, uterine fibroids, and adenomyosis. These conditions often …

Published: Jan. 22, 2025, midnight
Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.

Endometriosis (EM) is a widely recognized disorder in gynecological endocrinology. Although hormonal therapies are frequently employed for EM, their side effects and outcome limitations underscore the need to explore the …

Published: Jan. 22, 2025, midnight
Current research status and development trends of urinary tract endometriosis: a bibliometric analysis.

Endometriosis is a common gynecological disorder, with rising incidence rates and a decreasing age of onset, significantly affecting patients' quality of life and overall health. Urinary tract endometriosis (UTE) is …

Published: Jan. 22, 2025, midnight
Neutrophils initiate pro-inflammatory immune responses in early endometriosis lesion development.

Endometriosis is a chronic gynecological disease that affects 1 in 10 reproductive-aged women. Most studies investigate established disease; however, the initiation and early events in endometriotic lesion development remain poorly …

Published: Jan. 21, 2025, midnight
Mapping Human Uterine Disorders Through Single-Cell Transcriptomics.

Disruptions in uterine tissue function contribute to disorders such as endometriosis, adenomyosis, endometrial cancer, and fibroids, which all significantly impact health and fertility. Advances in transcriptomics, particularly single-cell RNA sequencing, …

Published: Jan. 21, 2025, midnight
Causal effects of genetically determined circulating metabolites on endometriosis: A Mendelian randomization study.

Endometriosis (EMs) is a common gynecological disease accompanied by metabolic disturbances. However, the causality between metabolites and the risk of EMs remains unclear. We conducted a 2-sample Mendelian randomization (MR) …

Published: Jan. 16, 2025, midnight
Drug for dry eyes offers hope for those with incurable gynecological condition - Hong Kong Standard

Drug for dry eyes offers hope for those with incurable gynecological condition Hong Kong Standard

Published: Jan. 15, 2025, 11:45 p.m.
The Current Applications of Metabolomics in Understanding Endometriosis: A Systematic Review.

Endometriosis is a common gynecological disease that affects approximately 10-15% of reproductive-aged women worldwide. This debilitating disease has a negative impact on the quality of life of those affected. Despite …

Published: Jan. 14, 2025, midnight
Silencing of FZD7 Inhibits Endometriotic Cell Viability, Migration, and Angiogenesis by Promoting Ferroptosis.

Endometriosis (EMS) is a difficult gynecological disease to cure. Frizzled-7 (FZD7) has been shown to be associated with the development of EMS, but its specific mechanism remains unclarified. This study …

Published: Jan. 11, 2025, midnight
β-elemene, a sesquiterpene constituent from Curcuma phaeocaulis inhibits the development of endometriosis by inducing ferroptosis via the MAPK and STAT3 signaling pathways.

The rhizome of Curcuma phaeocaulis Valeton, Curcuma wenyujin Y.H. Chen & C. Ling, or Curcuma kwangsiensis S. G. Lee et C. F. Liang, commonly known as Wen-E-Zhu and E'zhu, has …

Published: Jan. 10, 2025, midnight
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