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Efficacy of Organic Selenium Supplementation on Endometrioma Regression and Pain in Women With Endometriosis: A Triple-Blind Randomized Controlled Clinical Trial.

Endometriosis is a non-malignant, estrogen-dependent chronic inflammatory disorder that affects 10-15% of women during their reproductive years. Emerging evidence highlights the undeniable role of oxidative stress in the etiopathogenesis of …

Published: Oct. 10, 2025, midnight
Nationwide evaluation of hepatitis medication prescription patterns and costs in hepatitis B and C care.

The financial and healthcare burden of hepatitis B and C remains a significant challenge in Iran, despite efforts to control these diseases through vaccination and improved treatment protocols. This study …

Published: Oct. 10, 2025, midnight
NLRP3 Inflammasome in Gynecologic Inflammatory Diseases: Mechanisms, Pathophysiology, and Therapeutic Strategies.

The NOD-like receptor family containing pyridine domain 3 (NLRP3) inflammasome serves as a pivotal mediator of innate immune responses and a central driver of inflammatory processes. Upon detection of pathogenic …

Published: Oct. 10, 2025, midnight
The Diagnostic Performance of Transvaginal Ultrasound for Posterior Compartment Endometriosis Compared to Laparoscopic and Histopathological Findings: A Systematic Review.

Background: Deep infiltrating endometriosis (DIE) frequently affects the posterior pelvic compartment, where accurate non-invasive imaging is essential for diagnosis and surgical planning. Aim: This systematic review evaluates the diagnostic performance …

Published: Oct. 10, 2025, midnight
Identification and Validation of Iron Metabolism-Related Biomarkers in Endometriosis: A Mendelian Randomization and Single-Cell Transcriptomics Study.

Studies have shown that the iron concentration in the peritoneal fluid of women is associated with the severity of endometriosis. Therefore, investigation of iron metabolism-related genes (IM-RGs) in endometriosis holds …

Published: Oct. 9, 2025, midnight
Hope Medicine Completes Phase 2 Trial of Non-Hormonal Endometriosis Treatment - Femtech Insider

Hope Medicine Completes Phase 2 Trial of Non-Hormonal Endometriosis Treatment Femtech Insider

Published: Oct. 8, 2025, 7:30 p.m.
Case Report: A patient with lynch syndrome with vaginal endometriosis-associated malignancy and synchronous colonic tubulovillous adenoma.

Endometriosis is a common gynecological condition. However, endometriosis-associated malignancies occur in up to 1% of women with endometriosis. Most cases of endometriosis-associated malignancy occur in the ovary, whereas 20% of …

Published: Oct. 8, 2025, midnight
Insufficient NNMT promotes autophagy and disrupts progesterone signaling in endometrial stromal cells in recurrent implantation failure by modulating the H3K9me3-ALDH1A3 pathway - Nature

Insufficient NNMT promotes autophagy and disrupts progesterone signaling in endometrial stromal cells in recurrent implantation failure by modulating the H3K9me3-ALDH1A3 pathway Nature

Published: Oct. 7, 2025, 3:26 p.m.
TGFB1/SMAD3-Driven Macrophage-Myofibroblast Transition Promotes Fibrosis Progression in Endometriosis.

Endometriosis is a chronic gynecological disorder characterized by progressive fibrosis, which is closely associated with clinical symptoms such as dysmenorrhea and infertility. While myofibroblast activation is central to fibrogenesis, the …

Published: Oct. 7, 2025, midnight
Optimizing patient experiences and outcomes: proposal to develop an Endometriosis Care Quality Collaborative in the United States.

Published: Oct. 7, 2025, midnight
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