Endometriosis (EM) is an inflammatory condition that affects approximately 10% of the female-born population. It is characterized by the presence of endometrial tissue outside the uterine cavity, leading to chronic …
Endometriosis is an estrogen-dependent condition characterized by ectopic implantation of endometrial tissue, yet the molecular mechanisms underlying lesion persistence remain incompletely understood. Aquaporins (AQPs), transmembrane water channels involved in cellular …
To compare ablative energy technologies and evaluate their ability to destroy in vivo endometriosis tissue in humans.
Numerous abnormalities of the endometriosis eutopic endometrium contribute to the initiation and development of ectopic lesions. It is also believed that among the complex causes of the disease, systemic immunological …
Endometriosis and adenomyosis are prevalent chronic inflammatory conditions that significantly impact reproductive-age women, leading to debilitating symptoms such as pelvic pain, dysmenorrhea, and infertility. Endometriosis is characterized by ectopic endometrial …
This study investigateted the malignant transformation of endometriosis (EMS) into ovarian clear cell carcinoma (OCCC) using spatial transcriptomics and single-cell RNA sequencing (scRNA-seq) integration. Tissues with coexisting EMS and OCCC …
Endometriosis is a common gynaecological disorder characterised by the ectopic growth of endometrial-like tissue, which can lead to clinical symptoms such as chronic inflammation, pelvic pain, and infertility. Aberrant cellular …
Three-dimensional (3D) culture systems provide physiologically relevant models that better replicate in vivo cell architecture and function compared to the conventional two-dimensional cultures. In reproductive biology, 3D models of endometrial …
Endometriosis is a common estrogen-dependent disease marked by ectopic endometrial growth. Although the PI3K/AKT and kisspeptin pathways are known to regulate endometrial homeostasis, their interplay in disease progression remains unclear. …
Endometriosis is a chronic inflammatory disorder in which endometrial tissue grows outside the uterus, leading to pelvic pain and infertility. It remains a major challenge in women's health due to …