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Development of a three-dimensional culture model of endometrium to study embryo-uterine interactions.

Three-dimensional (3D) culture systems provide physiologically relevant models that better replicate in vivo cell architecture and function compared to the conventional two-dimensional cultures. In reproductive biology, 3D models of endometrial …

Published: Jan. 6, 2026, midnight
Evidence for KISS-1 nuclear translocation and PI3K/AKT signaling in the ultrastructurally and morphometrically analyzed human endometriosis.

Endometriosis is a common estrogen-dependent disease marked by ectopic endometrial growth. Although the PI3K/AKT and kisspeptin pathways are known to regulate endometrial homeostasis, their interplay in disease progression remains unclear. …

Published: Jan. 6, 2026, midnight
Artificial Intelligence in Gynecologic Imaging.

What was done? A review of artificial intelligence (AI) applications for the imaging of uterine fibroids, endometriosis, and adenomyosis. What was found? AI models can assist with the recognition, segmentation, …

Published: Jan. 6, 2026, midnight
The therapeutic potential of pirfenidone in alleviating fibrosis and restoring ovarian function in a novel ovarian endometriosis mouse model.

Published: Jan. 5, 2026, midnight
FTIR Spectroscopy Combined with Machine Learning Reveals Molecular Signatures Distinguishing three Phenotypes of Endometriosis.

Endometriosis is a chronic inflammatory disorder in which endometrial tissue grows outside the uterus, leading to pelvic pain and infertility. It remains a major challenge in women's health due to …

Published: Jan. 5, 2026, midnight
Endometriosis and Reproductive Sparing Surgery: A Narrative Review and AGREE II-S-Based Evaluation of International Guidelines.

Endometriosis is a complex disease that may affect a woman's fertility and quality of life. Owing to substantial variations in symptom severity, lesion distribution, and reproductive impact, its management presents …

Published: Jan. 4, 2026, midnight
Quantifying inflammatory resolution in human menstruation reveals disease-specific failure modes and enables a non-invasive diagnostic for endometriosis.

Inflammatory resolution is essential for tissue health, yet its dynamics remain difficult to study in humans. Menstruation is a recurrent, non-pathological inflammatory process that provides a natural window into inflammation …

Published: Jan. 4, 2026, midnight
Beyond VEGF and TGF-β: A Comprehensive Review of Growth Factor Pathways in the Pathophysiology of Uterine Leiomyomas.

Uterine leiomyomas or fibroids, are non-cancerous smooth muscle proliferations of the uterus, occurring mostly in women of reproductive age. Their pathogenesis involves complex growth factor interactions that regulate cellular proliferation, …

Published: Jan. 1, 2026, midnight
One-Class Genetic Algorithm for Authentication Analysis of Spectrochemical Data.

One-class classifier (OCC) models are widely applied to solve classification problems where control or class modeling from a target class is necessary. In this study, OCC models such as Data …

Published: Dec. 31, 2025, midnight
Research Advances in the Endometriotic Microenvironment: Synergistic Immune-Inflammatory-Angiogenic Interactions and their Therapeutic Translation.

Published: Dec. 29, 2025, midnight
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