A duo of redox-sensitive pore-loop cysteines controls the activity of the neural ion channel TRPM3.
Transient Receptor Potential Melastatin 3 (TRPM3) is a non-selective, Ca2+-permeable ion channel that plays a pivotal role in peripheral thermosensation and nociception. Moreover, gain-of-function variants in TRPM3 underlie a spectrum …
"I don't feel like me anymore": A large-scale qualitative study exploring body image disruption in endometriosis and adenomyosis.
This study explored the lived experiences of body image among individuals with a diagnosis or suspected diagnosis of endometriosis and/or adenomyosis. Using an online qualitative survey (n = 287) and …
Investigation of endothelin-1 receptor antagonist bosentan in a rat endometriosis model.
The study aimed to investigate the roles of endothelin-1 and endothelin receptors in a rat endometriosis model and to demonstrate how bosentan (BOS), an endothelin receptor blocker, could potentially serve …