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Pharmacophoric Investigation of a Natural Product-like Class of Aromatase Inhibitors Using Molecular Modeling.

Endometriosis is a condition affecting approximately 10% of reproductive-age women in which endometrial tissue is found in locations outside the uterus, often causing debilitating symptoms. Aromatase, an enzyme that also …

Published: Dec. 18, 2025, midnight
Ovarian squamous cell carcinoma: clinicopathological features, prognosis and immunotherapy outcomes.

To explore the characteristics and survival outcomes of ovarian squamous cell carcinoma (SCC) and the treatment effectiveness of immune checkpoint inhibitors (ICIs).

Published: Dec. 17, 2025, midnight
Endometriosis Involving the Bladder: A Contemporary Clinicopathologic Analysis of 88 Patients.

Predominantly, case reports and small case series of endometriosis involving the bladder have been published. This study aimed to provide a contemporary clinicopathologic analysis of a large cohort of patients …

Published: Dec. 17, 2025, midnight
APOL1-mediated kidney disease: a narrative review of the lessons learnt from the past 15 years.

Fifteen years have elapsed since the publication of the seminal work establishing the association between risk variants in the Apolipoprotein L1 (APOL1) gene and kidney disease in individuals of African …

Published: Dec. 17, 2025, midnight
Natural conception and successful delivery after laparoscopic uterine anastomosis for traumatic cervical separation: a case report.

Traumatic separation of the cervix from the body of the uterus is exceedingly rare, particularly as a complication of pelvic fractures. This condition often poses significant diagnostic and therapeutic challenges, …

Published: Dec. 17, 2025, midnight
Clinical Effectiveness and Cost-Effectiveness of Misoprostol in Comparison to Dilatation and Curettage for Treatment of First-Trimester Missed Abortion (Gestational Age ≤ 14 Weeks) in Iran.

The development of prostaglandins and antiprogestins revolutionized medical abortion by providing effective nonsurgical options for terminating pregnancy. Although both strategies are accepted in practice, variations in clinical efficacy, patient experiences, …

Published: Dec. 17, 2025, midnight
Anxiety and depression in women with endometriosis: A comparative study across fertility contexts.

To assess the prevalence of anxiety and depression in women with endometriosis undergoing ovarian stimulation and oocyte retrieval for IVF/ICSI or fertility preservation (FP) compared with women without endometriosis.

Published: Dec. 17, 2025, midnight
Thoracic Endometriosis Syndrome: A Systematic Review And Meta-analysis of Surgical Outcomes Among 1,182 patients over 25 years.

Without standardized guidelines, the management of thoracic endometriosis syndrome (TES) continues to fuel debate. Previous reviews have reported poor outcomes but lack data on complications, hospital length of stay (LOS) …

Published: Dec. 17, 2025, midnight
Borderline ovarian clear cell tumor arising from endometriosis during long-term dienogest therapy: a case report.

Endometriomas, commonly known as ovarian chocolate cysts, are a prevalent condition in women of reproductive age. They are cysts formed by the ectopic growth of endometrial tissue within the ovary, …

Published: Dec. 17, 2025, midnight
Patient-centered priorities in endometriosis and chronic pelvic pain: A mixed-methods and thematic analysis of intake narratives.

Understanding what patients prioritize when seeking care for endometriosis and chronic pelvic pain (CPP) is crucial for delivering personalized, responsive care. However, patient-defined goals remain poorly characterized across various life …

Published: Dec. 16, 2025, midnight
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