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Pembrolizumab plus chemotherapy in advanced or recurrent endometrial cancer: overall survival and exploratory analyses of the NRG GY018 phase 3 randomized trial - Nature.com

Pembrolizumab plus chemotherapy in advanced or recurrent endometrial cancer: overall survival and exploratory analyses of the NRG GY018 phase 3 randomized trial Nature.com

Published: March 5, 2025, 11:04 a.m.
Robotic multidisciplinary endometriosis surgery with multi-visceral resection: evaluation of short-term feasibility and safety outcomes.

Despite growing interest in robot-assisted surgery, the literature remains limited on the application of robotic surgery for complex endometriosis surgery requiring multidisciplinary input for multi-visceral resection. The aim of the …

Published: March 5, 2025, midnight
Does interdisciplinary group care for the treatment of endometriosis improve pain interference: protocol for a pilot randomised controlled trial at an urban academic medical centre.

Endometriosis affects 10-15% of people assigned female at birth and can cause chronic pelvic pain and impair many domains of quality of life, such as fertility, mood and bladder, bowel …

Published: March 5, 2025, midnight
Polygenic Scores for Dizygotic Twinning: Insights into the Genetic Architecture of Female Fertility.

Natural dizygotic twinning (DZT) results from hyper-ovulation and is considered an indicator of female fertility. DZT has low polygenicity, with only 0.20% of SNPs estimated to have a nonzero effect. …

Published: March 5, 2025, midnight
Endometrial immune Profiling and Precision Care Lead to Significantly Higher Live Birth Rates, MatriceLab Trial Shows - Yahoo Finance UK

Endometrial immune Profiling and Precision Care Lead to Significantly Higher Live Birth Rates, MatriceLab Trial Shows Yahoo Finance UK

Published: March 4, 2025, 8:05 a.m.
Endometrial immune Profiling and Precision Care Lead to Significantly Higher Live Birth Rates, MatriceLab Trial Shows - Yahoo Finance

Endometrial immune Profiling and Precision Care Lead to Significantly Higher Live Birth Rates, MatriceLab Trial Shows Yahoo Finance

Published: March 4, 2025, 8:05 a.m.
The Role of Mast Cells in the Development and Advancement of Endometriosis.

Endometriosis is a medical condition identified by the presence of endometrium-like tissue outside the uterus. This condition is known to result in symptoms such as frequent pelvic pain, infertility, and …

Published: March 4, 2025, 12:17 a.m.
Phosphatase and tensin homolog deficiency induces M2 macrophage polarization by promoting glycolytic activity in endometrial stromal cells.

Endometriosis is a common gynecological disorder, whose pathogenesis remains incompletely understood. Macrophages, a key type of immune cell, are pivotal in the context of endometriosis. This study seeks to explore …

Published: March 4, 2025, midnight
GRB2 regulation of essential signaling pathways in the endometrium is critical for implantation and decidualization.

Over 75% of failed pregnancies involve implantation defects. Growth factor receptor-bound protein 2 (GRB2) is an adaptor protein involved in signal transduction and cell communication. Here we show that the …

Published: March 4, 2025, midnight
MCP-1 promotes ILK phosphorylation at Ser246 during endometriosis development and affects the pregnancy outcome.

In women with endometriosis, monocyte chemoattractant protein 1 (MCP-1) or chemokine (C-C motif) ligand 2 (CCL2) is elevated in serum, peritoneal fluid, and endometriotic lesions, though its exact role in …

Published: March 4, 2025, midnight
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