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Reactive oxygen species signaling promotes lesion development in endometriosis through activation of the CHK1/SGK1 pathway.

Published: Oct. 27, 2025, midnight
Follicular Fluid Amino Acid Alterations in Endometriosis: Evidence for Oxidative Stress and Metabolic Dysregulation.

Background/Objectives: Endometriosis (EM) is a chronic gynecological condition associated with infertility, oxidative stress, and altered metabolic regulation. Follicular fluid (FF) reflects the microenvironment of the developing oocyte, and changes in …

Published: Oct. 27, 2025, midnight
Integrated bioinformatics analysis and machine learning identifies FZD4, SRPX2, and COL8A1 as angiogenesis hub genes in endometriosis.

This study aims to identify angiogenesis-associated genes (AAGs) in endometriosis (EM) by integrating bioinformatics analysis with machine learning, and to investigate their underlying mechanisms. Differentially expressed genes (DEGs) were screened …

Published: Oct. 26, 2025, midnight
RND3 Inhibits Endometriosis Progression by Regulating Autophagy and Oxidative Stress Through PLEKHG5.

Endometriosis (EMS) is a chronic gynecological disease. RND3 is recognized as a potential autophagy-related biomarker in EMS. The aim of this study was to investigate the regulatory role of RND3 …

Published: Oct. 26, 2025, midnight
Erratum: The Mechanism of Xuanyu Tongjing Decoction Regulating NOD/NFκB Pathway to Inhibit Ectopic Tissue Inflammation to Reduce Ovarian Damage in Rats with Ovarian Endometriosis [Corrigendum].

[This corrects the article DOI: 10.2147/DDDT.S500129.].

Published: Oct. 26, 2025, midnight
Mechanism of action of HuPoSan on EMs rats as revealed by multi-omics combined with network pharmacology.

Endometriosis (EMs) is a persistent inflammatory condition whose three main symptoms, mass, pain, and infertility, severely affect female patients of childbearing age. Hu-Po-San (HPS), a preparation consisting of various herbal …

Published: Oct. 26, 2025, midnight
The association between HPV infection and endometriosis: Risk and fertility outcomes.

While infections have been implicated in endometriosis pathogenesis, the role of human papillomavirus (HPV) remains unclear. This study combined a meta-analysis of seven studies with a case-control study ( n …

Published: Oct. 25, 2025, midnight
Laparoscopic excision of the sciatic nerve endometriosis.

The case concerns a forty-year-old patient with adenomyosis, metrorrhagia, and typical sciatic pain during menstruation. After the insertion of an LNG-IUD, the bleeding stopped, but the sciatic pain persisted. MRI …

Published: Oct. 25, 2025, midnight
Pelvic Puzzles: Imaging Non-Traumatic Emergencies of the Female Pelvis: A Comprehensive Review.

Acute non-traumatic pelvic pain represents a frequent and complex diagnostic dilemma in pre-menopausal females presenting to the emergency department due to overlapping symptomatology across pregnancy and non-pregnancy related causes. Radiologists …

Published: Oct. 25, 2025, midnight
Serum Galectin-1 as a Diagnostic Biomarker in Endometriosis: A Prospective Longitudinal Study.

Endometriosis is a chronic condition characterized by the presence of endometrial-like tissue outside the uterine cavity. It affects ~10% of reproductive-aged individuals and is associated with dysmenorrhea and infertility. Although …

Published: Oct. 25, 2025, midnight
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