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Molecular mechanisms in endometriosis: linking JAK/STAT pathway, ferroptosis, and microbial dysbiosis.

Endometriosis is a chronic gynaecological disorder characterized by ectopic endometrial growth, inflammation, pain, and infertility. Current therapies, largely hormonal and surgical, have limited efficacy and compromise fertility, underscoring the need …

Published: Feb. 14, 2026, midnight
First Dates Ireland couple announce pregnancy on Late Late Show - RSVP Live

First Dates Ireland couple announce pregnancy on Late Late Show RSVP Live

Published: Feb. 13, 2026, 10:52 p.m.
Misdiagnosis rate of endometriosis and strategies employed to identify endometriosis by analyzing patient characteristics in low-resource settings.

Endometriosis is a major gynecologic health issue affecting ~10% of women and girls of reproductive age worldwide. Despite its high prevalence, no curative treatment exists. Early diagnosis and treatment are …

Published: Feb. 13, 2026, midnight
From Endometriosis to Encapsulation: A Case Report of Endometriosis Causing Sclerosing Encapsulating Peritonitis.

Sclerosing encapsulating peritonitis is a rare complication of endometriosis that has sparsely been described in the literature. It involves the development of a thick gray-white fibrotic membrane, which partially or …

Published: Feb. 13, 2026, midnight
Exploring the therapeutic potential of disulfiram in endometriosis: mechanisms targeting inflammation, oxidative stress, pyroptosis, and angiogenesis.

Endometriosis (EMS) is a prevalent, inflammatory gynecological disorder with limited effective treatments and high recurrence rates. Given the central roles of inflammation, oxidative stress, pyroptosis, and angiogenesis in its pathogenesis, …

Published: Feb. 12, 2026, midnight
Atypical gelation of Elagolix sodium in aqueous media: Mechanistic insights and Inhibition via coamorphization.

Elagolix sodium (ELS), a non-peptide oral gonadotropin-releasing hormone receptor (GnRH) antagonist approved for the treatment of endometriosis-associated pain, displays atypical gelation in aqueous environments along with challenging physical properties such …

Published: Feb. 12, 2026, midnight
2-Deoxyglucose dendrimer-enabled niclosamide delivery to FRβ-expressing macrophages alleviates endometriosis progression and associated hyperalgesia.

Endometriosis is a chronic, incurable disease. Due to limited efficacy, high recurrence rates, and serious side effects of current treatments, development of new, targeted, non-hormonal therapies is urgently needed. We …

Published: Feb. 12, 2026, midnight
Impact of lesion size and localization on symptom severity in intestinal endometriosis.

Intestinal endometriosis (IE) often presents with dyschezia, gastrointestinal (GI) dysfunction, dyspareunia, and dysmenorrhea. The impact of lesion localization and size on the severity of symptoms remains insufficiently studied, complicating preoperative …

Published: Feb. 12, 2026, midnight
Building a foundation to promote Women's health research in Dubai. Study protocol for a project to investigate the feasibility of establishing a dedicated Women's health biobank.

Women's health concerns play a role in several of the UAE's major public health challenges, including cardiovascular disease, injuries, cancer, and respiratory conditions. The UAE's 2024 National Policy for improving …

Published: Feb. 12, 2026, midnight
Amygdalin inhibits 17β-estradiol-induced mesenchymal transition through TGF- β/Smad signaling in normal and endometriotic endometrial epithelial cells.

Endometriosis is a common gynecological disorder characterized by chronic pelvic pain, infertility, and systemic symptoms, with currently limited treatment options. Amygdalin, a cyanogenic glycoside derived from bitter apricot kernels, has …

Published: Feb. 11, 2026, midnight
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