Can patient-derived organoid models be reliably established from diverse surgical phenotypes of endometriosis, and how do clinical factors such as hormonal treatment affect their growth success and morphology?
Endometriosis is a chronic and estrogen-dependent disorder that affects about 10% of women of reproductive age worldwide. Endometriosis has been associated with chronic inflammation and an atherogenic lipid profile, two …
Ovarian cancer (OC) is highly lethal, largely due to late diagnosis and chemoresistance. Endometriosis (EM) increases the risk of specific OC subtypes, but the molecular connection between the two diseases …
Endometriosis is diagnosed in 25% to 40% of infertile patients. This disease can affect ovarian reserve and oocyte quality, as a result Assisted Reproductive Technology is often required. However, the …
Sexological interviews in gynecological consultations remain a practice that is not routinely undertaken despite the importance of sexual health. The objectives of this study were to investigate patients' expectations from …
Endometriosis is a common gynecological disorder among women of reproductive age worldwide. This study aims to examine global patterns of endometriosis disease burden among reproductive-aged women and to evaluate its …
Endometriosis is a gynecological disorder that affects 190 million reproductive age women worldwide. Laparoscopic surgery is considered the gold standard to diagnose the disease, creating a barrier to diagnosis and …
Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of ovarian endometriomas …
Endometriosis (EMs) and depression are both common conditions that have a significant negative impact on quality of life. However, it is still unclear about the relationship between them. The study …
Adenomyosis occurs when endometrial glands and stroma grow within the uterine myometrium. As a clinically significant disease, adenomyosis causes substantial pelvic pain and heavy menstrual bleeding. It remains understudied due …