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Stage-specific autophagy dynamics in reproductive processes and associated disorders.

Autophagy is a highly conserved eukaryotic process that degrades cytoplasmic material within lysosomes, and plays a crucial role in cellular development, function and homeostasis. Recent studies have increasingly revealed the …

Published: July 28, 2025, midnight
Role of AMP-Activated Protein Kinase (AMPK) in Female Reproduction: A Review.

The adenosine monophosphate (AMP)-activated protein kinase (AMPK) signalling pathway regulates cell metabolism, inflammation and the immune response. This signalling pathway is essential for maintaining reproductive homeostasis and influencing steroidogenesis, implantation, …

Published: July 16, 2025, midnight
Functions of RhoA in the female reproductive system.

The Ras homolog gene family member A (RhoA) is a small GTPase. RhoA plays major roles in cytoskeletal regulation, transcriptional control, and cell cycle maintenance. RhoA is widely expressed in …

Published: May 15, 2025, midnight
The role of gut and vaginal microbiomes in reproductive health: Implications for PCOS, endometriosis, pre-eclampsia, and beyond.

The interplay between the gut microbiome and reproductive health has gained increasing attention in recent years. Emerging research suggests that imbalances in the gut microbiome may impact reproductive function through …

Published: April 7, 2025, midnight
Postpartum Depression in Patients with Chronic Migraine: A Retrospective, Observational Analysis.

Purpose: To evaluate how migraine impacts the risk for postpartum depression (PPD) in women of reproductive age as well as the effect of comorbidities on this risk. Methods: This is …

Published: April 2, 2025, midnight
Endometriosis Severity and Risk of Preeclampsia: A Combined Mendelian Randomization and Observational Study.

Endometriosis has been hypothesized to increase the risk of preeclampsia (PE) and eclampsia, although the exact mechanism of this relationship is not clear. This study aimed to further explore the …

Published: March 27, 2025, midnight
The Role of Exosomal miRNAs in Female Infertility: Therapeutic Potential and Mechanisms of Action.

Reproductive disorders, including preeclampsia (PE), endometriosis, premature ovarian failure (POF), and polycystic ovary syndrome (PCOS), present substantial challenges to women's reproductive health. Exosomes (EXOs) are cell-derived vesicles containing molecules that …

Published: March 24, 2025, midnight
Cesarean Section and Its Impact on Uterine Artery Resistance and the Risk of Pre-eclampsia in Subsequent Pregnancies.

The purpose of the current study was to compare the color Doppler findings of uterine arteries and perinatal outcomes in pregnant women with and without previous cesarean section (C/S).

Published: Jan. 22, 2025, midnight
Engineering nanosystems for regulating reproductive health in women.

Reproductive health-related diseases have a significant impact on the well-being of millions of women worldwide, severely compromising their quality of life. Women encounter unique challenges in terms of reproductive health, …

Published: Jan. 1, 2025, midnight
Social Determinants of Health and Lifestyle Risk Factors Modulate Genetic Susceptibility for Women's Health Outcomes.

Women's health conditions are influenced by both genetic and environmental factors. Understanding these factors individually and their interactions is crucial for implementing preventative, personalized medicine. However, since genetics and environmental …

Published: Dec. 14, 2024, midnight
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