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Multi-Target Modulation of Interconnected Pathogenetic Pathways by Natural Bioactive Compounds in Endometriosis.

Endometriosis is a chronic estrogen-dependent disease characterized by the presence of endometrial-like tissue outside the uterine cavity. Its pathogenesis involves interactions between inflammatory, angiogenic, hormonal, oxidative stress-related, and cell survival-associated …

Published: Aug. 13, 2026, midnight
Fascin-Centred Invasive Competence in Eutopic Endometrium: A Hypothesis-Driven Narrative Review of Endometriosis Pathogenesis and Non-Surgical Biomarker Potential.

Endometriosis is a chronic, oestrogen-responsive inflammatory disease characterised by endometrial-like tissue outside the uterine cavity. Because retrograde menstruation is common, lesion establishment probably requires cellular competence and a permissive ectopic …

Published: Aug. 13, 2026, midnight
MiR-29c-3p Impairs the Adhesion of Endometrial Epithelial Cells via COL4A1/β-catenin in Endometriosis.

Defective endometrial receptivity is an indispensable cause of infertility in endometriosis, yet the post-transcriptional regulatory mechanisms underlying this impairment remain poorly understood. The goal of this research was to describe …

Published: Aug. 12, 2026, midnight
Exosomal miR-21-5p from ectopic endometrial stromal cells drives fibrosis progression in endometriosis through direct VHL targeting.

Ovarian endometriosis is a chronic inflammatory disease characterized by extensive tissue remodeling and fibrosis, which significantly impacts female reproductive health. This study demonstrates that ectopic endometrium (Ect) in patients with …

Published: Aug. 12, 2026, midnight
Integrated lipidomics and transcriptomics reveal the key role of ceramides in the development of endometriosis.

Endometriosis (EMs) is a chronic gynecological disease with poorly understood pathogenesis. This study integrated lipidomics and transcriptomics to systematically investigate aberrant sphingolipid metabolism in EMs, aiming to identify pathogenic mechanisms …

Published: Aug. 11, 2026, midnight
A Rare Mimicker: Renal Endometriosis and Its Diagnostic Pitfalls-Review of Reported Cases.

Background/Objectives: Primary renal endometriosis with extrapelvic locations of endometriosis lesions is deemed extremely rare. Therefore, the aim of this review was to assess the current literature on renal endometriosis, encompassing …

Published: Aug. 11, 2026, midnight
[The Laterality of Endometriosis].

Endometriosis, affecting 10-15% of women of reproductive age, is more commonly found on the left side of the pelvis. This laterality phenomenon's etiology remains obscure. We reviewed the existing literature …

Published: Aug. 7, 2026, midnight
Endometrial cells with high ALDH activity contribute to uterine development and regeneration.

Adult stem cells are thought to drive the regenerative potential of the endometrium and contribute to the pathogenesis of endometriosis; however, their identity and defining features remain to be characterized. …

Published: Aug. 6, 2026, midnight
A novel tRNA-derived fragment, tRF-19-79MP9PJZ, promotes uterine corpus endometrial carcinoma progression by targeting DSC3.

Uterine corpus endometrial carcinoma (UCEC) ranks as the 6th most common malignancy among women. Emerging evidence indicates that the dysregulation of tRNA-derived fragments (tRFs) is involved in the pathogenesis of …

Published: Aug. 6, 2026, midnight
A Diagnostic Dilemma in a Breast Cancer Patient on Tamoxifen: Perihepatic Endometriosis Masquerading as Metastatic Disease.

Breast cancer metastasis to the liver carries a poor prognosis, and the identification of hypermetabolic hepatic or perihepatic lesions on 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in a patient …

Published: Aug. 6, 2026, midnight
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