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Relugolix's impact on endometriosis-associated pain and quality of life: a meta-analysis of EHP-30 outcomes.

Relugolix offers a promising alternative for endometriosis-associated pain, yet its comprehensive impact on health-related quality of life (HRQoL), particularly as measured by the disease-specific EHP-30 questionnaire, remains underexplored.

Published: Sept. 29, 2025, midnight
Optimising Hormonal Therapy Before Declaring Failure in Endometriosis-Associated Pain.

Published: Sept. 24, 2025, midnight
The role of pre-operative gonadotrophin-releasing hormone agonists (GnRHa) on pain, bowel and bladder symptoms in rectovaginal/colorectal endometriosis surgery: a multicenter cohort study.

The efficacy of medical and surgical treatment of endometriosis-associated pain is a source of ongoing controversy. There is a lack of evidence about gonadotropin-releasing hormone agonists (GnRHa) use on long-term …

Published: Sept. 23, 2025, midnight
The ExPAND Study: A Prospective Association Study into Endometriosis-Associated Pain, Neurosteroid Synthesis, and TRPM3.

Endometriosis-associated pain has debilitating effects on the quality of life of patients. Despite its high prevalence in reproductive-aged women, the pathophysiology is still unknown, impeding the development of targeted treatment …

Published: Sept. 23, 2025, midnight
Acupuncture combined with Chinese herbal medicine versus Chinese herbal medicine alone to improve clinical efficacy in treating endometriosis-associated pain: a systematic review and meta-analysis - Frontiers

Acupuncture combined with Chinese herbal medicine versus Chinese herbal medicine alone to improve clinical efficacy in treating endometriosis-associated pain: a systematic review and meta-analysis Frontiers

Published: Sept. 19, 2025, 2:04 p.m.
Tolerability and Shared Decision-Making in the Hormonal Management of Endometriosis-Associated Pain.

Background: The management of endometriosis-associated pain has traditionally focused on analgesic efficacy. However, with high-level evidence demonstrating therapeutic equivalence among principal hormonal classes, the paradigm has shifted towards a patient-centred …

Published: Sept. 18, 2025, midnight
Relugolix's Impact on Endometriosis-Associated Pain and Quality of Life: A Meta-Analysis of EHP-30 Outcomes - Frontiers

Relugolix's Impact on Endometriosis-Associated Pain and Quality of Life: A Meta-Analysis of EHP-30 Outcomes Frontiers

Published: Sept. 12, 2025, 5:59 p.m.
Efficacy of Elagolix and Relugolix for the Treatment of Pelvic Pain in Patients With Endometriosis: A Systematic Review.

Endometriosis is a chronic gynecological condition commonly associated with pelvic pain, dysmenorrhea, dyspareunia, and infertility. Owing to the limitations and adverse effects of traditional hormonal therapies, this study aimed to …

Published: Sept. 12, 2025, midnight
Pain pathways and stem cells in endometriosis pathogenesis.

As a gynecological disease, endometriosis is a disease in which pain and inflammation are important parts. Endometriosis is a chronic, estrogen-related situation with a multifactorial etiology that remains incompletely understood. …

Published: Sept. 3, 2025, midnight
Neuroinflammation is responsible for pain in endometriosis - targeting the JAK-STAT pathway and mast cell activation.

Chronic pain is a defining feature of endometriosis and contributes significantly to the diminished quality of life observed in affected individuals. Despite advances in understanding disease pathology, current therapeutic strategies …

Published: Aug. 29, 2025, midnight
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