Uterine leiomyomas or fibroids, are non-cancerous smooth muscle proliferations of the uterus, occurring mostly in women of reproductive age. Their pathogenesis involves complex growth factor interactions that regulate cellular proliferation, …
Abnormal uterine bleeding (AUB), particularly when associated with uterine leiomyomas, is a frequent cause of iron deficiency anemia among women of reproductive age. While commonly manageable, in rare instances, AUB …
We systematically examined the current literature on staged pre-hysterectomy uterine artery embolization (SUAE) for symptomatic uterine fibroids.
Endometriosis with ovarian cysts is common in reproductive-age women and contributes to pain and infertility. The influence of age on clinical and surgical outcomes remains uncertain. This retrospective study analyzed …
Autoimmune and inflammatory rheumatic diseases (RDs) are more prevalent in women and often affect gynecological health. Particularly, heavy menstrual bleeding (HMB) and dysmenorrhea are more common in patients with RD. …
Uterine fibroids are highly prevalent and constitute significant health and social concerns, particularly among black-African women of reproductive age. However, beyond the clinical burden, there is limited data on the …
Steroid receptor coactivators (SRCs) are master regulators of nuclear receptor signaling and play essential roles in female reproductive physiology. By integrating steroid hormone signaling with growth factors and metabolic pathways, …
Gynecologic disorders, such as cervical and ovarian tumors, uterine fibroids, and endometriosis, present significant clinical challenges due to frequent recurrence, emerging chemoresistance, and undesirable effects associated with prolonged hormonal treatments. …
Ectopic pregnancy (EP) and tubal endometriosis (TEM) directly affect the fallopian tube structure and function, while ovarian cysts (OC) and uterine fibroids (UF) may indirectly influence tubal physiology. These conditions …
Menopause represents a cardio-metabolic transition, but cardiovascular (CV) health in women is highly influenced by other reproductive milestones and conditions, which delineate a cardio-reproductive lifeline. Reproductive history represents an opportunity …