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A comprehensive treatment algorithm for chronic pelvic pain patients: A perspective review and future guidelines.

Chronic pelvic pain is one of the most prevalent syndromes in family medicine, gynecology, and urology. Chronic pelvic pain patients are often misdiagnosed and have unnecessary prolonged suffering. Both misdiagnosis …

Published: April 25, 2026, midnight
Microbiota-metabolite axis in endometriosis: Pathogenic mechanisms and clinical implications.

Growing evidence highlights the role of microbiota, including those of the gut, reproductive tract, and endometrial tissue, as critical functional drivers in the pathogenesis of endometriosis (EM). Studies have revealed …

Published: April 25, 2026, midnight
Individualized fertility preservation counselling for women with endometriosis-a systematic review.

Endometriosis is a chronic disease that may require surgical intervention under certain circumstances. Although the condition itself is associated with impaired fertility in 30-50% of affected individuals, surgical treatment may …

Published: April 22, 2026, midnight
Macrophage membrane-biomimetic nanovehicles delivering amygdalin halt pyroptosis propagation and alleviate endometriosis-associated neuropathic pain.

The clinical management of endometriosis encounters a significant obstacle: existing therapies inadequately address both the inhibition of ectopic lesion proliferation and the mitigation of the neuroinflammation associated with chronic pain. …

Published: April 20, 2026, midnight
Exploring the mechanisms of luteolin in treating polycystic ovary syndrome and endometriosis via network pharmacology, molecular docking, and molecular dynamics simulation.

This study aims to elucidate the molecular mechanisms underlying luteolin's therapeutic effects on polycystic ovary syndrome (PCOS) and endometriosis (EM), thereby providing a theoretical foundation for developing novel treatment strategies. …

Published: April 18, 2026, midnight
Medical and Surgical Management of Endometriosis: A Narrative Review of Clinical Outcomes.

Endometriosis is a chronic, estrogen-dependent, and heterogeneous gynecologic disorder associated with persistent pain, infertility, and substantial impairment in quality of life (QoL), necessitating individualized and evidence-based management. This narrative review …

Published: April 16, 2026, midnight
The efficacy of ultrasound-guided treatment of ovarian endometriosis cysts: A meta-analysis.

The purpose of this meta-analysis was to systematically assess the efficacy of ultrasound-guided therapy of ovarian endometriosis cyst (OEC). Several databases were searched to gather published studies on the efficacy …

Published: April 15, 2026, midnight
Novel insights into the role of Annexin A2 signaling pathway in female reproductive system diseases: from mechanisms to advanced therapies.

Annexin A2 (ANXA2) is a calcium-dependent protein with high affinity for phospholipids, and its multifunctional nature has drawn increasing attention in the onset and progression of various disorders of the …

Published: April 14, 2026, midnight
Unravelling Multilayered RNA Modification Networks in Female Reproduction and Obstetric/Gynaecologic Disorders.

Background/Objective: RNA modifications, including N6-methyladenosine (m6A), 5-methylcytosine (m5C), 7-methylguanosine (m7G), N1-methyladenosine (m1A), pseudouridine (Ψ), N4-acetylcytidine (ac4C), 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) and adenosine-to-inosine (A-to-I) editing, constitute a critical layer of post-transcriptional regulation that …

Published: April 13, 2026, midnight
The inclusion of sex and gender considerations and female representation in Nutrition and Dietetics journals: A comparison between 2012 and 2022.

Consideration of sex and gender in nutrition research is needed to inform best practice interventions and policy. It is unknown how nutrition and dietetic journals comply with sex and gender …

Published: April 9, 2026, midnight
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