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Demographic and hematological differences between endometriosis and menorrhagia in Saudi women: A retrospective observational study of 946 patients.

Endometriosis and menorrhagia are prevalent gynecological conditions with overlapping symptoms, yet comparative data from Middle Eastern populations remain scarce. We aimed to comprehensively characterize demographic and hematological differences between these …

Published: March 28, 2026, midnight
Revealing the immune landscape of menstrual blood: unlocking insights into activation, exhaustion, and mitochondrial mass for reproductive health.

Reproductive disorders such as endometriosis and polycystic ovary syndrome (PCOS) are increasingly recognized as immune-mediated conditions, yet their immunopathology remains poorly understood. Menstrual blood, a noninvasive and biologically relevant sample, …

Published: March 27, 2026, midnight
Charting the nerve-immune axis in endometriosis.

Endometriosis is increasingly recognized as a systemic disorder involving complex interactions between nerves and immune cells, driving chronic pain and inflammation beyond the initial theories. Recent breakthroughs highlight aberrant sensory …

Published: March 26, 2026, midnight
Comparing psychological distress, health-related quality of life and pain in individuals diagnosed with endometriosis and suspected to have endometriosis: A cross-sectional analysis.

To assess whether pain, psychological distress, and health-related quality of life (HRQoL) differ in individuals diagnosed with endometriosis and those suspected to have endometriosis.

Published: March 26, 2026, midnight
Catheter-Directed Sclerotherapy Versus Ovarian Cystectomy for Unilateral Ovarian Endometrioma: A Pilot Randomized Controlled Trial.

Background: Ovarian cystectomy is standard treatment for endometrioma but is associated with decreased ovarian reserve. Catheter-directed sclerotherapy (CDS) is an ovary-sparing image-guided alternative; however, supporting evidence comprises retrospective comparative and …

Published: March 25, 2026, midnight
Global epidemiology of ovarian cancer: patterns, trends, and risk factors.

Ovarian cancer was the eighth most frequently diagnosed cancer among women in 2022. The global age-standardized incidence rate of ovarian cancer decreased from 7.22/100,000 to 6.71/100,000 from 1990 to 2021. …

Published: March 24, 2026, midnight
Serum neurofilament light chain in fibromyalgia: comparative evidence of neuronal injury across chronic pain conditions.

Evidence increasingly shows small nerve fibre pathology in subsets of people with fibromyalgia through skin biopsy, corneal confocal microscopy, and microneurography. However, blood-based biomarkers of ongoing neuronal damage, particularly neurofilament …

Published: March 24, 2026, midnight
Risk Factors of Adolescent Endometriosis Onset and Recurrence: A Retrospective Study.

This study aimed to identify adolescent-specific risk factors for endometriosis onset and postoperative recurrence to facilitate early identification and risk stratification.

Published: March 24, 2026, midnight
Endometrial epithelial cells with high ALDH activity control uterine development and regeneration.

Adult stem cells are thought to drive the regenerative potential of the endometrium and contribute to the pathogenesis of endometriosis, however, their identity and defining features remain to be characterized. …

Published: March 24, 2026, midnight
Understanding women's decisions to seek an endometriosis diagnosis: A Health Belief Model approach.

Early diagnosis of endometriosis is crucial, yet limited literature exists on factors influencing women's decisions to seek diagnosis. This study explores the role of symptoms, health beliefs, and social influences …

Published: March 23, 2026, midnight
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