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Endometriosis as a chronic endothelial disorder: thromboinflammation, vascular reprogramming, and systemic cardiovascular risk.

Microvascular thromboinflammation is a pervasive yet under-recognized driver of multisystem morbidity that links focal endothelial injury to distal organ dysfunction through interacting cellular and plasmatic networks. Contemporary paradigms remain fragmented: …

Published: June 30, 2026, midnight
Analysis of Drug Clinical Trials in Obstetrics and Gynecology: A Five-Year Retrospective Study from a Public Tertiary Specialty Hospital in China.

Women remain underrepresented in clinical drug development despite their unique biological characteristics and growing disease burden. In China, this disparity is particularly concerning given the rising incidence of gynecologic conditions …

Published: June 30, 2026, midnight
Lipid accumulation product and endometriosis in women aged 18 years and older: A cross-sectional study of NHANES 1999 to 2006.

Endometriosis, a chronic gynecological disorder, is increasingly linked to metabolic dysregulation. The lipid accumulation product (LAP) - a biomarker integrating waist circumference and triglycerides - may provide additional information on …

Published: June 28, 2026, midnight
Associations between atherogenic index of plasma and endometriosis: The National Health and Nutrition Examination Survey 1999 to 2006.

It has been proved that lipids have an effect on endometriosis, and the plasma atherosclerosis index (AIP), as a new lipid index, has not been proved to be correlative to …

Published: June 28, 2026, midnight
Real-Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis.

Endometriosis is a common gynecological disorder characterized by the ectopic growth of endometrium-like tissue outside the uterine cavity and is associated with pelvic pain, infertility, and reduced quality of life. …

Published: June 26, 2026, midnight
The Circadian-Light-Hygiene Hypothesis: A Potential Modulator of Fertility and Birthrate Trends.

Human fertility has declined sharply since 1950, and a growing body of evidence suggests that while conventional socioeconomic factors are well-established drivers of the broader demographic transition, they do not …

Published: June 26, 2026, midnight
Indications and Efficacy of Progestogen-Monotherapy as Menopause Hormone Therapy: A Narrative Review.

Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen …

Published: June 25, 2026, midnight
Diagnostic Performance of Saline/Gel Sonovaginography in Assessment of Deep Infiltrating Endometriosis at Posterior Compartments; A Systematic Review and Meta-Analysis.

Sonovaginography (SVG) is a specialized ultrasound technique for evaluating certain locations of deep endometriosis (DE) in the posterior compartments. In this study, we assessed the diagnostic accuracy of saline/gel SVG …

Published: June 25, 2026, midnight
Peritoneal Incretin Deficiency and Tirzepatide as a Multi-Axis Adjuvant Hypothesis in Treatment-Refractory Endometriosis: A Mechanistic Framework Linking Metabolism, Immunity, Fibrosis, and Nociception.

Endometriosis is increasingly recognized as a chronic systemic disorder extending beyond the classical estrogen-dependent paradigm, integrating metabolic, immune, fibrotic, and nociceptive pathways that sustain lesion persistence and refractory pelvic pain. …

Published: June 24, 2026, midnight
Hyaluronic Acid Enriched Medium for Embryo Transfer: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis of randomized controlled trials (RCTs) evaluated whether the use of hyaluronic acid (HA)-enriched medium for embryo transfer (ET) improves live birth rates in in-vitro fertilization …

Published: June 23, 2026, midnight
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