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3D map-guided modeling of functional endometrial tissue using multi-compartment assembloids.

The human endometrium is a dynamic tissue that lines the uterus and undergoes constant remodeling, making it especially susceptible to gynecological diseases like endometriosis and endometrial cancer. The molecular mechanisms …

Published: Aug. 23, 2025, midnight
Expression profiles of E-cadherin and N-cadherin in endometriosis and other gynecological diseases towards targeted treatment: a systematic review.

This systematic review aimed to summarize all available data and evaluate the roles of E-cadherin, N-cadherin, associated molecules, and signaling pathways in the pathogenesis of endometriosis. The search was conducted …

Published: Aug. 21, 2025, midnight
Unveiling the vital role of OGG1 in inflammation, vascular endothelial damage, and cell death in obstetric and gynecological diseases.

The DNA repair enzyme 8-oxoguanine DNA glycosylase-1 (OGG1) plays a crucial role in the initiation of DNA base excision repair pathway by recognizing and excising the oxidative base lesions including …

Published: Aug. 14, 2025, midnight
Global, regional, and national prevalence and trends of gynecological diseases among women of childbearing age from 1990 to 2021: An analysis of the global burden of disease study 2021.

The global prevalence and trends of gynecological diseases (GDs) among women of childbearing age (WCBA) remain unclear and may be underestimated. This study aims to evaluate the prevalence of GDs …

Published: Aug. 1, 2025, midnight
Rectal Clear Cell Carcinoma Arising from Endometriosis: Case Report and Literature Review.

Background and Clinical Significance: Endometriosis is a common gynecological disease that can occasionally be associated with malignant transformation. The most common site of malignant transformation is the ovary, but there …

Published: July 31, 2025, midnight
Endometriosis-Associated Periodontal Disease: A Large Cohort Perspective Study.

Endometriosis is a chronic estrogen-dependent gynecological disease affecting millions of women worldwide. Besides its well-established impact on reproductive health, emerging evidence suggests a potential association between endometriosis and periodontal disease. …

Published: July 26, 2025, midnight
Effects of vitamin supplementation on related symptoms in women with endometriosis: a systematic review and meta-analysis.

Endometriosis is a gynecological disease with high occurrence, and symptoms include dysmenorrhea, infertility, and dyspareunia, which seriously affect women's quality of life. Antioxidants are beneficial in improving the symptoms of …

Published: May 26, 2025, midnight
Gut microbiome in patients with early-stage and late-stage endometriosis.

Endometriosis is a chronic inflammatory gynecological disease. Previous studies have explored relationships between endometriosis and the microbiota, but none have focused on differences in gut microbiota between early-stage and late-stage …

Published: April 7, 2025, midnight
The health-promoting lifestyle and its relationship with the impacts of endometriosis on women's lives in Iran, 2022: a cross-sectional study.

Endometriosis is a chronic gynecological disease that affects various aspects of the women's lives, so considering its impacts and improving health-promoting lifestyle is important. The present study aimed to determine …

Published: April 2, 2025, midnight
Characterization of key genes and immune cell infiltration associated with endometriosis through integrating bioinformatics and experimental analyses.

Endometriosis (EM) is the most common gynecological disease in women of childbearing age. This study aims to identify key genes and screen drugs that may contribute to EM treatment.

Published: March 31, 2025, midnight
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