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Identification and Validation of a Four-Gene Signature as a Novel Potential Diagnostic Biomarker Panel for Endometriosis: Causal and Mechanistic Insights from Mendelian Randomization and Bioinformatics.

Endometriosis (EMS) is an estrogen-dependent disease that can lead to chronic pain and infertility. Small ubiquitin-related modifier (SUMO)ylation, a key post-translational modification, has been demonstrated to be associated with endometrial …

Published: Aug. 3, 2026, midnight
Microplastics and female infertility: reproductive toxicity and underlying mechanisms.

In modern society, the progression of ovarian aging in women has accelerated, and the incidence of infertility has increased markedly with a distinct younger-onset trend. Exploring the etiology and pathogenesis …

Published: Aug. 3, 2026, midnight
Dietary and Environmental Exposure to Toxic Elements in Endometriosis: A Missing Piece of the Etiological Puzzle?

Background/Objectives: Endometriosis is a chronic estrogen-dependent disease with a complex and incompletely understood etiology. Environmental exposure to toxic elements, including cadmium, lead, mercury, and arsenic, may contribute to its development …

Published: Aug. 2, 2026, midnight
Superficial Peritoneal Endometriosis Beyond Surgical Diagnosis: A Narrative Review of Emerging Functional and Molecular Perspectives.

Background and Objectives: Superficial peritoneal endometriosis (SPE) remains one of the most difficult endometriosis phenotypes to diagnose non-invasively, because lesions are frequently small, multifocal, and poorly detectable using conventional imaging. …

Published: Aug. 2, 2026, midnight
H.C. Wainwright cuts Karyopharm stock rating on trial miss By Investing.com - Investing.com UK

H.C. Wainwright cuts Karyopharm stock rating on trial miss By Investing.com Investing.com UK

Published: Aug. 1, 2026, 6:38 a.m.
Expression Profiling of Immune-Related Genes in Different Samples from Patients with Endometriosis Revealed Upregulation of THBS1, CHGB and CYR61.

Endometriosis is a chronic, inflammatory, estrogen-dependent disease that affects approximately 6-10% of women of reproductive age. The present study aimed to investigate the expression of 48 immune-related genes in different …

Published: Aug. 1, 2026, midnight
H.C. Wainwright cuts Karyopharm stock rating on trial miss By Investing.com - Investing.com Australia

H.C. Wainwright cuts Karyopharm stock rating on trial miss By Investing.com Investing.com Australia

Published: July 31, 2026, 11:35 a.m.
Karyopharm shares crater on second Phase 3 flop for Xpovio in endometrial cancer - Endpoints News

Karyopharm shares crater on second Phase 3 flop for Xpovio in endometrial cancer Endpoints News

Published: July 31, 2026, 10:42 a.m.
Imaging of Thoracic Manifestations of Obstetric and Gynecologic Disease.

Cardiothoracic involvement by obstetric and gynecologic pathologic conditions creates a broad spectrum of clinical and radiologic manifestations, ranging from mild to critical. The authors describe the unique and often unrecognized …

Published: July 31, 2026, midnight
Proposals for the #Enzian addendum and update: an international expert survey for item generation.

Accurate and standardised characterisation of endometriosis extent is essential for patient counselling regarding pain and fertility outcomes, surgical planning, multidisciplinary communication, and clinical research. The Enzian classification has been applied …

Published: July 31, 2026, midnight
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