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[Therapeutic Education Program for Endometriosis: An Eight-Year Retrospective.].

Endometriosis is a chronic disease affecting approximately one in ten women of reproductive age. In cases of chronic pain associated with impaired quality of life, a multidisciplinary and integrative approach …

Published: Oct. 10, 2025, midnight
Mechanism of vascular endothelial growth factor regulating hypoxia and inflammatory microenvironment in endometriosis: based on bioinformatics and multi-level validation.

Endometriosis remains a prevalent gynecological disorder that affects women during their reproductive years, featured by progressive inflammation and enhanced HIF-1α expression. This paper intended to plumb the mechanism of vascular …

Published: Oct. 10, 2025, midnight
Functions of Estrogen and Estrogen-Related Receptors in Diseases of the Female Reproductive System.

Diseases of the female reproductive system are prevalent. These conditions often have a high proportion of asymptomatic patients and prolonged treatment durations. Estrogen, a crucial steroid hormone, plays a central …

Published: Oct. 10, 2025, midnight
NLRP3 Inflammasome in Gynecologic Inflammatory Diseases: Mechanisms, Pathophysiology, and Therapeutic Strategies.

The NOD-like receptor family containing pyridine domain 3 (NLRP3) inflammasome serves as a pivotal mediator of innate immune responses and a central driver of inflammatory processes. Upon detection of pathogenic …

Published: Oct. 10, 2025, midnight
The Diagnostic Performance of Transvaginal Ultrasound for Posterior Compartment Endometriosis Compared to Laparoscopic and Histopathological Findings: A Systematic Review.

Background: Deep infiltrating endometriosis (DIE) frequently affects the posterior pelvic compartment, where accurate non-invasive imaging is essential for diagnosis and surgical planning. Aim: This systematic review evaluates the diagnostic performance …

Published: Oct. 10, 2025, midnight
Progestagens for pain symptoms associated with endometriosis.

Endometriosis is a hormone-sensitive inflammatory condition affecting between 5% and 10% of reproductive-aged women and an unknown number of gender-diverse individuals. It is often associated with debilitating pelvic pain symptoms. …

Published: Oct. 9, 2025, midnight
Minimal clinically important changes of patient-reported outcome measures for acute post-surgical pain.

Patient-Reported Outcome Measures (PROMs) are essential instruments for assessing post-surgical pain-related outcomes from the patient's perspective. The concept of minimal clinically important difference (MCID) aims to identify the smallest change …

Published: Oct. 9, 2025, midnight
Comparison of the short-term effects of dienogest and oral contraceptives on pain and quality of life in women with endometriosis: a systematic review and meta-analysis.

To compare the short-term effects of dienogest and oral contraceptives (OCPs) on pain and quality of life in women with endometriosis.

Published: Oct. 9, 2025, midnight
Risk of endometriosis, adenomyosis and related symptoms among female offspring according to conception by assisted reproductive technologies.

To study the relationship between conception by ART and risk of endometriosis/adenomyosis in female offspring.

Published: Oct. 9, 2025, midnight
Plant-based bioactives and oxidative stress in reproduction: anti-inflammatory and metabolic protection mechanisms.

Oxidative stress plays a central role in reproductive disorders, with food bioactive compounds offering therapeutic potential through their antioxidant properties. This review examines antioxidant active ingredients from plant-based foods and …

Published: Oct. 9, 2025, midnight
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