Central sensitization in women with endometriosis: a cross-sectional study.
Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain. Central sensitization, a form …
Abuse history as a modifier of symptom phenotype in endometriosis: Insights from a multidimensional retrospective cohort.
Endometriosis is a heterogeneous pain condition with variable symptom expression. Abuse history has been associated with amplified pain, gastrointestinal symptoms, and central sensitization in varying populations; however, whether these effects …
VIDEO ARTICLE Retrorectal Endometriotic Lesion Involving Sacral Roots ........Surgical Technique for Nerve-Sparing Excision and Pain Relief.
To present a laparoscopic nerve-sparing technique for the excision of a retrorectal fibrotic lesion involving the sacral roots (S2-S4), with additional dissection of the lumbosacral trunk based on the patient's …
Metabolomics Analysis Reveals Gut Microbiota-Associated Sakuranin Modulates Endometrial Stem Cell Differentiation and Inflammation to Alleviate Pain in Endometriosis.
Endometriosis (EMS) is characterized by pain symptoms that seriously affect patients' quality of life. Gut microbiome-related metabolites (GMRM) play an important role in the process of EMS. However, the role …