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Associations of PFAS exposure with obstetric and birth outcomes in the Japan Environment and Children's Study (JECS): Is maternal endometriosis an effect modifier?

Per- and polyfluoroalkyl substances (PFAS) are reportedly associated with adverse obstetric outcomes, including premature labor and gestational diabetes. We aimed to evaluate associations of maternal PFAS exposure with obstetric and …

Published: Nov. 6, 2025, midnight
Sonographic and Clinical Progression of Adenomyosis and Coexisting Endometriosis: Long-Term Insights and Management Perspectives.

Objectives: To evaluate the impact of hormonal therapy on the evolution of painful symptoms in premenopausal women with adenomyosis, with or without concomitant endometriosis, over an 18-month follow-up period. This …

Published: Nov. 6, 2025, midnight
Metabolome analysis as a potential source of endometriosis biomarkers with the use of multiomics approach in its diagnosis.

Endometriosis poses diagnostic challenges. This study aimed to analyze the metabolomic profiles of plasma and peritoneal fluid samples obtained from women with endometriosis compared to controls. Our multicenter study involved …

Published: Nov. 5, 2025, midnight
Ferroptosis in reproductive system disorders: Pathological roles and therapeutic potential.

Ferroptosis, as an iron-dependent programmed cell death, plays a significant role in reproductive system diseases. It's involved in the pathological processes of various reproductive system diseases by affecting the survival …

Published: Nov. 5, 2025, midnight
Nanodrug impact on female reproductive health and fetal development: From translation approaches to long-term safety concern.

Biomaterials for drug delivery offer significant advantages over conventional medications, including enhanced cellular uptake, improved drug stability, targeted delivery, and controlled drug release. Cutting-edge nanodrugs delivery approaches such as drugs …

Published: Nov. 5, 2025, midnight
Altered miR-410-3p and Target Genes (PCDH8, VEGFA, NUMB) Expression in Ovarian Endometriosis: A Case-Control Study.

Endometriosis is a condition in which tissue similar to the endometrium grows outside the uterus. Angiogenesis plays an important role in endometriosis development. Bioinformatics analysis indicates that miR-410-3p is involved …

Published: Nov. 5, 2025, midnight
Altered Apoptosis in Endometriosis Compared with Ovarian Carcinoma.

Background and Objectives: Endometriosis has been shown to be associated with an increased cancer risk, and apoptosis may be important in the pathophysiology of endometriosis. To date, it remains unclear …

Published: Nov. 5, 2025, midnight
Catamenial pneumothorax with histologically proven diaphragmatic endometriosis successfully managed by combined surgical resection and hormonal therapy: A four-year recurrence-free case.

Catamenial pneumothorax (CP) is a rare form of spontaneous pneumothorax associated with thoracic endometriosis. We report a case of CP with histologically proven diaphragmatic endometriosis successfully managed by combined surgical …

Published: Nov. 5, 2025, midnight
Psychoneuroendocrine Associations with Momentary Pelvic Pain in Endometriosis.

Endometriosis is a gynecological condition which often causes chronic or recurrent pelvic pain (CPP). The disease can thereby impose a significant burden on affected individuals and their romantic relationships. Existing …

Published: Nov. 4, 2025, midnight
Identified endoplasmic reticulum stress-related molecular cluster and immune characterization in endometriosis.

Endometriosis is a common disease among women of childbearing age, and endoplasmic reticulum stress (ERS), a response involved in regulating protein homeostasis, has been linked to its pathogenesis. To identify …

Published: Nov. 4, 2025, midnight
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