Latest Articles

Study on biomarkers associated with epigenetic factors in endometriosis combining transcriptome with experimental validation.

Endometriosis (EM) is a disease related to reproductive dysfunction. The mechanism of epigenetic factors (EF) in EM still needs to be studied. Emerging evidence suggests that EF plays a role …

Glycomic Insights in Gynecological Disease: From Molecular Mechanisms to Precision Diagnostics and Therapeutics.

Gynecological diseases-encompassing polycystic ovary syndrome, endometriosis, infertility, and malignancies-represent a significant global health burden affecting women's quality of life, reproductive capacity, and long-term health outcomes. While traditional diagnostics rely on …

The Hidden Link Between Endometriosis and Obesity: A State-of-the-Art Review.

Endometriosis remains an under-researched disease with a wide range of symptoms. Endometriosis reduces a woman's quality of life and professional productivity, yet its exact causes, risk factors, and treatment have …

Cognitive and electrophysiological biomarkers of endometriosis with versus without chronic pelvic pain.

Despite endometriosis impacting at least 10% of women globally, with most self-reporting chronic pelvic pain (CPP) and cognitive difficulties, research reporting on objective cognitive disruptions remains extremely limited, although recent …

PARP-1 couples β-catenin/TCF4 signaling to epithelial-mesenchymal transition in endometriosis.

Safety and efficacy of hormonal therapies used to treat endometriosis in women suffering migraine.

Hormonal therapy is the cornerstone of long-term endometriosis management, especially for women deferring surgery. In patients with comorbid migraine - a common, disabling condition - therapeutic choices must balance efficacy …

Therapeutic Effects of Vitamins in Endometriosis Patients: A Systematic Review of Randomized Controlled Trials.

Endometriosis is a chronic, estrogen-dependent inflammatory condition affecting approximately 10% of women of reproductive age worldwide. It is characterized by the presence of endometrial-like tissue outside the uterine cavity, which …

Association of Peripheral Inflammatory Markers with Conception Outcomes Among Women with Endometriosis-Associated Infertility.

Background: Predicting natural conception following surgical treatment remains a clinical challenge for endometriosis, a chronic inflammatory condition often associated with infertility. This study aimed to determine if simple, low-cost inflammatory …

Modulation of gut microbiota and short-chain fatty acids by probiotics attenuates inflammation in endometriosis.

This study investigated whether probiotics alleviate Endometriosis (EMs)-related inflammation by modulating the gut microbiota and short-chain fatty acids (SCFAs).

Activity-Selectivity of Flavonoid Derivatives in Endometriotic Cells.

Natural polyphenolics, more specifically flavonoids and derivatives, constitute chemically versatile scaffolds with a broad biological potential. In this study, different flavonoid derivatives (1-37) were assessed for cytotoxicity in Ishikawa and …