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Natural bioactive compounds: Properties and health advantages against numerous medical conditions with a special focus on endometriosis management.

Natural bioactive compounds, such as curcumin, polyphenols, and flavonoids are important in the prevention and treatment of lifestyle disorders like diabetes, cancer, and heart disease. Their immunomodulatory, antiviral, antioxidant, and …

Published: June 17, 2026, midnight
NMR-based serum metabolite and lipoprotein profiling for endometriosis across clinically relevant and physiological comparator settings: assessment of diagnostic utility and exploratory biological signals.

Reliable non-invasive biomarkers for endometriosis remain unavailable in routine practice, and their translational value depends on performance in symptomatic referral populations rather than only against healthy controls. We evaluated Nuclear …

Published: June 17, 2026, midnight
NK Cell Profiling: Expression of TIGIT and LAG3 as Immune Checkpoints in Advanced Endometriosis.

Endometriosis (EMS) is a gynecological condition that is associated with chronic pelvic pain and inflammation. Evidence supports the idea that natural killer (NK) cell dysfunction contributes to EMS pathogenesis; nevertheless, …

Published: June 16, 2026, midnight
A transdiagnostic cognitive model of depression and anxiety in chronic inflammatory disease: Evidence from multiple sclerosis and endometriosis.

Depressive and anxiety symptoms are prevalent in Multiple Sclerosis (MS) and Endometriosis (EMS), yet their underlying processes remain poorly understood. Guided by a transdiagnostic framework (Nolen-Hoeksema & Watkins, 2011), this …

Published: June 14, 2026, midnight
Emerging Pathways to Non-Invasive Diagnosis in Endometriosis: Integrating Machine Learning, Deep Learning and Multi-Omics Biomarkers.

Endometriosis is a chronic, debilitating condition affecting approximately 10-15% of reproductive-aged women and it is often associated with significant diagnostic delays due to its heterogeneity and unreliable non-invasive tests. Artificial …

Published: June 12, 2026, midnight
Luoshi Neiyi prescription mitigates endometriosis by modulating nuclear receptor subfamily 5 group A member 1 methylation.

This study aimed to investigate the mechanisms underlying Nuclear Receptor Subfamily 5 Group A Member 1 (NR5A1, encoding SF-1) hypomethylation in endometriosis (EMs) and to evaluate the effects of Luoshi …

Published: June 11, 2026, midnight
Exploring the potential of gut microbiota metabolites in the treatment of endometriosis through network pharmacology and Mendelian randomization.

Studies have shown that dysregulation of the gut microbiota (GM) plays a crucial role in the development of endometriosis (EMs). Study aimed to investigate the potential of protective GM metabolites …

Published: June 11, 2026, midnight
Identification and diagnostic potential of pyroptosis-related genes in endometriosis: A novel bioinformatics analysis and validation.

Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic endometrial growth. This study aimed to identify and analyze potential signatures of pyroptosis-related genes in EMs.

Published: June 9, 2026, midnight
Breaking the endometriosis-stroke axis: lesion-focused hydrogel reprogramming of thromboinflammatory networks.

Endometriosis is a chronic, systemic inflammatory disorder characterized by the ectopic implantation of endometrial-like tissue and accompanied by persistent pain and infertility. Beyond the pelvis, accumulating epidemiological evidence indicates that …

Published: June 8, 2026, midnight
Gut microbiota dysbiosis in endometriosis: mechanistic insights and gut microbiota-targeted therapeutic strategies.

Endometriosis (EMs) is a prevalent, estrogen-dependent gynecological disorder characterized by the ectopic implantation and proliferation of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of reproductive-aged women globally. Despite …

Published: June 5, 2026, midnight
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