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Pathway to Endometriosis Diagnosis in South Australia: A Qualitative Study.

Endometriosis is a significant and prevalent health issue. Delayed diagnosis is common and the associated delay to treatment is associated with high socioeconomic and personal costs including chronic pain, infertility …

Published: Nov. 11, 2025, midnight
Pharmacologic Interventions for Endometriosis-Related Pain: A Systematic Review and Meta-analysis.

(Abstracted from Obstet Gynecol 2025;146(2):e23-e35) An estimated 10% to 15% of women who are of reproductive age are affected by endometriosis, defined as abnormal growth of endometrium-like tissue outside of …

Published: Nov. 7, 2025, midnight
In vitro fertilization-assisted pregnancy combined with high-intensity focused ultrasound treatment in patients with endometriosis and adenomyosis with successful pregnancy: a case report.

High-intensity focused ultrasound ablation has emerged as a noninvasive therapeutic option for adenomyosis of the uterus. We studied a female with infertility patient to explore the application of in vitro …

Published: Nov. 5, 2025, midnight
Ultrasound-guided ethanol sclerotherapy versus laparoscopic surgery for endometriomas: a randomized clinical trial in a real-world setting.

To compare the efficacy of ultrasound-guided alcohol sclerotherapy versus laparoscopic cystectomy for the management of ovarian endometriomas, focusing on complications, recurrence, pain relief, and healthcare costs.

Published: Nov. 4, 2025, midnight
Effect of Different Female Factors on Pregnancy Rates in Artificial Insemination With Donor Sperm Cycles: A Prospective Observational Study.

Background Artificial insemination with donor sperm (AID) is an established treatment option for various indications. The outcome of such treatment is likely to be affected by different female factors and …

Published: Nov. 3, 2025, midnight
Effect of kisspeptin, neurokinin, and dynorphin neurons on regulation of reproduction.

Gonadotropin-releasing hormone pulsatility is under the influence of hypothalamic neuropeptides, especially neurons expressing kisspeptin, neurokinin B, and dynorphin. These hypothalamic cells are called KNDy neurons. By integrating hormonal and environmental …

Published: Nov. 1, 2025, midnight
Lactate-mediated immune suppression and MDSC expansion in endometriosis: Mechanisms and nanoparticle-targeted therapies.

Endometriosis, a chronic gynecological disorder characterized by the ectopic growth of endometrial-like tissue, is associated with severe pelvic pain, infertility, and profound immune dysregulation. Despite advances in hormonal therapy and …

Published: Nov. 1, 2025, midnight
Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway.

Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome proliferator‑activated receptor α (PPARα) and …

Published: Oct. 31, 2025, midnight
From Gut to Reproductive Health: Exploring Microbiome Interactions and Future Interventions.

Recent advances in microbiome research have illuminated the complex bidirectional interactions between gut health and reproductive well-being. Understanding the gut microbiome's influence on the reproductive system and vice versa reveals …

Published: Oct. 31, 2025, midnight
MicroRNAs Regulating Oxidative Stress in Human Fertility: A Narrative Review of Mechanistic Insights and Clinical Potential.

Human infertility represents a multifaceted condition, with oxidative stress (OS) and microRNAs (miRNAs) emerging as key contributors to its pathophysiology. This comprehensive review explores the complex interplay between reactive oxygen …

Published: Oct. 31, 2025, midnight
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